Study of the influence of supplementation of additives with high content of polyunsaturated fatty acids capable of potentiating the effect of probiotics on modulation of metabolic and reproductive processes in animals

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Identifier1/0476/16
Funding schemeScientific grant agency (Ministry of education, science, research and sport of the Slovak Republic)
Principal investigator at UVLFSopková Drahomíra, doc. MVDr., PhD.
Project duration01.01.2016 – 31.12.2019
The scientific project deals with influence on metabolic profile, concentration of essential fatty acids in blood and tissues and on reproductive abilities of model animals of diet supplemented with combination of probiotics and flaxseed containing higher level of n-3 polyunsaturated fatty acids and fibres. Results of our study will help to increase body of knowledge about mechanism of effect of synbiotics and ways of increasing their efficacy. The use of natural additives could directly increase quality and safety of food of animal origin for humans. In experiments conducted in vitro we will observe changes in expression of proliferation and apoptotic markers, secretion of hormones and other signal substances by ovarian cells and their responses to addition of physiological regulators. The obtained results could contribute to innovation of methods of reproductive regulation, development of functional feeds, foodstuffs and medicines intended for animal production and consumption by animals and humans.