In vitro immunological selection of probiotic bakterial strains for using in prevention of intestinal infectious diseases
| Identifier | 1/0483/15 |
|---|---|
| Funding scheme | Scientific grant agency (Ministry of education, science, research and sport of the Slovak Republic) |
| Principal investigator at UVLF | Levkutová Mária, prof. MVDr., PhD. |
| Project duration | 01.01.2015 – 31.12.2017 |
In the project we will be under in vitro conditions tested the immunostimulatory properties of selected strains of probiotic bacteria in culture with immunocompetent cells (eg PMBC). For co-cultivation will be used specific modulator (Salmonella enterica respectively. Campylobacter spp.) and non-specific
stimulant -Concanavalin A. The values of expression of proinflammatory and anti-inflammatory cytokines and chemokines will demonstrate the immunological properties of selected probiotic strains. Strains with the best immunological properties will be presented for their use in practice.
Partners
- University of Veterinary Medicine and Pharmacy in Košice (Project coordinator)