CLASSICAL, GENOMIC AND PROTEOMIC APPROACH IN THE INVESTIGATION OF ECONOMICALLY IMPORTANT VIRAL INFECTIONS OF FARM ANIMALS

In this project the viral infections of farm animals as PMWS, PRRS and pestivirus infections will be studied using integrated application of classical as wel as genomic and proteomic techniques. Experiments will be oriented to reveal epizootiological situation in pig and cattle farms, the investigation of immunonological parameters in infected animals, the role of cytokines in infectious process. The co-infections in pigs (PCV-2, PRRSV, TTV, PTV, boca-like virus) will be the subject of study as well. Molecular events in infected cells as differential gene expresssion and synthesis of proteins will be studied using the microarray technique and proteomic methods.