The perspective of the use of beneficial bacteria and their bioactive substances in the prevention and therapy of oral diseases in companion animals

Oral diseases represent a serious therapeutic problem not only in human but also in veterinary medicine. Above all, diseases caused by the presence of pathogenic bacteria in the form of dental biofilm, such as periodontitis and dental caries, are a medical challenge for veterinarians and an important area of interest in terms of their prevention and therapy in companion animals. Due to the increase in the prevalence of multidrug-resistant pathogenic bacteria, which significantly limits the use of antibiotics, alternative strategies are constantly being sought in the prevention and therapy of these diseases. Beneficial bacteria and their bioactive substances can be one of the potential possibilities. Based on this, the presented project is focused on the study of the antimicrobial effect of potentially beneficial bacteria and their bioactive substances, namely bacteriocins, biosurfactants and exopolysaccharides, against oral pathogens of companion animals. The obtained results will contribute to the expansion of knowledge in the field of research into the prospective use of beneficial bacteria and bioactive substances in the prevention and therapy of oral diseases of companion animals, while overall results can help to develop more effective preparations as an innovative approach in the management of oral diseases in veterinary medicine.