The potential of bioactive substances produced by beneficial bacteria in the prevention and therapy of dental diseases in veterinary and human medicine

Dental diseases, especially dental caries and periodontal diseases, represent a health issue and a medical challenge in terms of their prevention and therapy in both human and veterinary medicine. Pathogenic bacteria in the dental biofilm involved in the development and progression of these diseases are more resistant to common antimicrobial substances. A promising alternative strategy is the use of bioactive substances produced by beneficial bacteria. The presented project is focused on obtaining of bioactive substances such as bacteriocins, biosurfactants and exopolysaccharides from oral bacteria, which are highly effective against selected oral pathogens. The achieved results will expand the knowledge in the field of the potential of bioactive substances use and in the future they may also contribute in the development of highly effective and at the same time non-toxic alternative preparations based on these substances in the prevention and therapy of dental diseases in both veterinary and human medicine.