Analysis of blood serum proteins in the evaluation of the internal environment and diagnosis of animal diseases

Many health disorders and pathological processes are associated with changes in blood serum protein concentrations, their proportion and occurrence of dysproteinemias. The determination of total serum protein concentrations is the basic laboratory method for the evaluation of proteins in serum or plasma also in animals. Changes in the concentrations of one or more of proteins need not to express in altered total serum protein concentrations. By pathological serum protein concentrations and suspected dysproteinemias it is necessary to perform further analyses, including serum protein electrophoresis and the determination of selected specific serum proteins. Specific serum protein analyses are in the veterinary medicine rarely used laboratory methods in the evaluation of the type and forms of dysproteinemias. Many serum proteins may be diagnostically important. From this reason, many of them may be used as special biomarkers in the evaluation of various serious diseases and health disorders also in animals.