Blood serum proteins as important biomarkers in the diagnosis of animal health

The metabolic and immunologic responses of the organism caused by pathological processes include also the production of various protein substances by the altered cells and tissues that may leak into the body fluids, where they may be objectively measured. By some diseases, these substances may be used in the diagnostic process indicating the presence of pathological process. From this reason, they are usually called as biomarkers of diseases. Furthermore, they play important role by the evaluation of disease process, objectively indicate the clinical state of the patient and the effectiveness of therapy, suggest the extent and severity of lesions, and may have predictive or prognostic value. The objective of the proposed project is to extend and further develop the panel of laboratory examinations in animals for novel innovative biomarkers and health indicators that could improve the diagnostic process of several several animal diseases.