The monitoring of selected lichen metabolites on the angiogenesis, tumor cell proliferation and pathogenic yeast growth
| Identifier | 1/0071/21 |
|---|---|
| Funding scheme | Scientific grant agency (Ministry of education, science, research and sport of the Slovak Republic) |
| Principal investigator at UVLF | Bačkorová Miriam, doc. RNDr., PhD. |
| Project duration | 01.01.2021 – 31.12.2023 |
The main topic of this project is to find out the effects of extracts from various lichen species and their components on angiogenesis, tumor cell proliferation and the growth of pathogenic yeasts of Candida and Malassezia. Angiogenesis will be studied by the in ovo method in the chicken and Japanse quail embryo chorioallantoic membrane (CAM model). The antiproliferative effect will be tested in vitro on the tumor cell lines. Antimycotic activity will be determined by reference and isolate species of Candida albicans and Malassezia pachydermatis.