Effect of interaction between mycotoxins and adsorbents on immune system of poultry

In our climate zone the most important group of mycotoxins are fusarium mycotoxins. They are divided into trichothecenes, fumonizine and zearalenone. These toxic substances after absorption in GIT induce lesions in different target organs. Damage of the tissue is followed by local and/or systemic immune response. One of the way to eliminate mycotoxins in GIT is the application of adsorbents into feed. Effect of adsorbents with interaction of mycotoxins on the local and systemic immune response is not well known. Combination of morphological methods used at the study of intestinal mucose and proliferative activity – apoptosis enterocytes, electron microscope at the determination of changes in the target cells, immunological methods studying the local and systemic immune response and moleculo genetics methods at the quantification of the cytokine response at the interaction mycotoxin- adsorbent will give more information about the effect of mycotoxins on the organism with simmultaneous application of adsorbents.