Study of the mechanism of action of flax seed on functions of female gonads and uterus of animals

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Identifier1/0204/20
Funding schemeScientific grant agency (Ministry of education, science, research and sport of the Slovak Republic)
Principal investigator at UVLFVlčková Radoslava, doc. MVDr., PhD.
Project duration01.01.2020 – 31.12.2023
The aim of the present project is to investigate and clarify the effect of flax seed on ovarian and uterine functions of various animal species. During the project, changes in the expression of proliferative and apoptotic markers, several receptors, secretion of hormones and various signal substances and changes in their response to superior and local regulators will be observed in in vitro experiments on cultured equine and porcine ovarian cells and in vivo experiments on ovarian structures of gilts. Differences in composition of follicular fluid and in uterine structure, density and localization of receptors for selected hormones will be observed.

Project outputs

  1. ANDREJČÁKOVÁ, Zuzana - VLČKOVÁ, Radoslava - SOPKOVÁ, Drahomíra - KOZIOŁ, Katarzyna - KOZIOROWSKI, Marek - FABIÁN, Dušan - ŠEFČÍKOVÁ, Zuzana - HOLOVSKÁ, Katarína - ALMÁŠIOVÁ, Viera - SIROTKIN, Alexander V. Dietary flaxseed's protective effects on body tissues of mice after oral exposure to xylene. In: Saudi journal of biological sciences. 2021. ISSN 1319-562X, Vol. 28, no. 7 (2021), p. 3789-3798. (2021: 4.052 - IF, 62 - H-index, 4.247 - IF 5y, 0.656 - SJR, Q1 - SJR Best Q, Q2 - JCR Best Q, 0.55 - ABDC).

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