Influence of contaminants - products of the oil industry on the ovarian functions of various animal species. The use of medicinal plants to reduce the effect of these contaminants
| Identifier | 1/0392/17 |
|---|---|
| Funding scheme | Scientific grant agency (Ministry of education, science, research and sport of the Slovak Republic) |
| Principal investigator at UVLF | Vlčková Radoslava, doc. MVDr., PhD. |
| Name of the project’s principal investigator | zástupca vedúceho projektu |
| Project duration | 01.01.2017 – 31.12.2020 |
The aim of the submitted project is to obtain information on the possible effects of environmental contaminants - products of the oil industry on the ovarian functions of various animal species, as well as on the possibilities of preventing the adverse effects of certain medicinal plants and plant substances. The aim of the project is to clarify the impact of contaminants and plant substances on the reproduction of laboratory and farm animals and to understand the mechanism of their effect. During the project, in vivo and in vitro experiments on cultured ovarian cells of mice, horses, cattle, and pigs exposed to the products of the oil industry (benzene, xylene, toluene), extract from medicinal plants and plant substances (yuka, chia, daidzein, diosgenin) and combinations of contaminants environment with plant extracts and substances, observed changes in reproductive parameters, expression of proliferative and apoptotic markers, secretion of hormones and other signaling substances and their responses to gonadotropin FSH additions.