In vitro immunological selection of probiotic bakterial strains for using in prevention of intestinal infectious diseases

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Identifier1/0483/15
Funding schemeScientific grant agency (Ministry of education, science, research and sport of the Slovak Republic)
Principal investigator at UVLFLevkutová Mária, prof. MVDr., PhD.
Project duration01.01.2015 – 31.12.2017
In the project we will be under in vitro conditions tested the immunostimulatory properties of selected strains of probiotic bacteria in culture with immunocompetent cells (eg PMBC). For co-cultivation will be used specific modulator (Salmonella enterica respectively. Campylobacter spp.) and non-specific stimulant -Concanavalin A. The values of expression of proinflammatory and anti-inflammatory cytokines and chemokines will demonstrate the immunological properties of selected probiotic strains. Strains with the best immunological properties will be presented for their use in practice.

Partners

  • University of Veterinary Medicine and Pharmacy in Košice (Project coordinator)