Virome of gastrointestinal tract:of pigs and wild boars: Identification and analysis of virus agentssamostatný vedecký pracovník

This project is focused on the identification and analysis of viruses infecting gastrointestinal tract of diarrheic and healthy pigs and wild boars. Research will be oriented on highly dangerous viruses as TGEV, PEDV, rotaviruses with high socio-economical impact as well as on new emerging viruses as for example hokovirus, kobuvirus, sapoviruses and others. The complex analysis of virome in enteric samples will be carried out using new method as NGS with potential of discovery of new viruses. The genomes of identified viruses will be studied using bioinformatic tools to reveal unique motifs as insertions, deletions, mutations. The study will also cover evolution of viruses at the molecular level and application in molecular epidemiology. Viruses with zoonotic character (virus of hepatitis E) will be studied in pigs and in incriminated part of human population.