Oral administration of inosine promotes recovery after experimental spinal cord injury in rat

CARDOSO, Fellipe Soares dos Santos - MARIA, Guilherme dos Santos - PESTANA, Fernanda Marques - CARDOSO, Ricardo - RAMALHO, Bruna dos Santos - HERINGER, Luiza dos Santos - TABOADA, Tiago Bastos - MARTINEZ, Ana Maria Blanco - DE ALMEIDA, Fernanda Martins. Nerve repair with polylactic acid and inosine treatment enhance regeneration and improve functional recovery after sciatic nerve transection. In FRONTIERS IN CELLULAR NEUROSCIENCE, 2025, vol. 18, no., pp. Dostupné na: https://doi.org/10.3389/fncel.2024.1525024.

DOS SANTOS, Beatriz - PIERMARTIRI, Tetsade - TASCA, Carla I. The impact of purine nucleosides on neuroplasticity in the adult brain. In Purinergic Signalling, 2025-02-01, 21, 1, pp. 113-131. ISSN 15739538. Dostupné na: https://doi.org/10.1007/s11302-024-09988-9.

LI, Binglun - WU, Qiong - TAN, Hui - WU, Tao - CUI, Yanchao. Effectiveness of activity-based interventions for improving independence and mobility in spinal cord injury: a meta-analysis. In DISABILITY AND REHABILITATION, 2025, vol. 47, no. 19, pp. 4904-4912. ISSN 0963-8288. Dostupné na: https://doi.org/10.1080/09638288.2025.2468346.

CARDOSO, Fellipe Soares dos Santos - MARIA, Guilherme dos Santos - PESTANA, Fernanda Marques - CARDOSO, Ricardo - RAMALHO, Bruna dos Santos - HERINGER, Luiza dos Santos - TABOADA, Tiago Bastos - MARTINEZ, Ana Maria Blanco - DE ALMEIDA, Fernanda Martins. Nerve repair with polylactic acid and inosine treatment enhance regeneration and improve functional recovery after sciatic nerve transection. In Frontiers in Cellular Neuroscience, 2024-01-01, 18, pp. ISSN 16625102. Dostupné na: https://doi.org/10.3389/fncel.2024.1525024.

CARDOSO, R. - CARDOSO, F.S.D. - RAMALHO, B.D. - MARIA, G.D. - CAVALCANTI, R.R. - TABOADA, T.B. - DE ALMEIDA, J.S. - MARTINEZ, A.M.B. - DE ALMEIDA, F.M. Inosine Improves Functional Recovery and Cell Morphology Following Compressive Spinal Cord Injury in Mice. In NEUROTRAUMA REPORTS. ISSN 2689-288X, 2024, vol. 5, no. 1, p. 957-968.

DOS SANTOS, Beatriz - PIERMARTIRI, Tetsade - TASCA, Carla I. The impact of purine nucleosides on neuroplasticity in the adult brain. In Purinergic Signalling, 2024-01-01, pp. ISSN 15739538. Dostupné na: https://doi.org/10.1007/s11302-024-09988-9.

DE ALMEIDA, Fernanda Martins - MARQUES, Suelen Adriani - RODRIGUES DOS SANTOS, Anne Caroline - PRINS, Caio Andrade - DOS SANTOS CARDOSO, Fellipe Soares - HERINGER, Luiza dos Santos - MENDONCA, Henrique Rocha - BLANCO MARTINEZ, Ana Maria. Molecular approaches for spinal cord injury treatment. In NEURAL REGENERATION RESEARCH, 2023, vol. 18, no. 1, pp. 23-30. ISSN 1673-5374. Dostupné na: https://doi.org/10.4103/1673-5374.344830.

KULKARNI, Neeraj - SHINDE, Suchita Dattatray - MAINGLE, Mohit - NIKAM, Darshani - SAHU, Bichismita. Reactive oxygen species-responsive thymine-conjugated chitosan: Synthesis and evaluation as cryogel. In International Journal of Biological Macromolecules, 2023-07-01, 242, pp. ISSN 01418130. Dostupné na: https://doi.org/10.1016/j.ijbiomac.2023.125074.

MA, Lili - MU, Ying - LI, Xiangqing - ZHANG, Ming - AN, Wenhan - ZENG, Fanshuo. Expression of transforming growth factor-beta 1 and autophagy markers in the bladder of rats with neurogenic lower urinary tract injury. In SPINAL CORD, 2023, vol. 61, no. 2, pp. 154-159. ISSN 1362-4393. Dostupné na: https://doi.org/10.1038/s41393-022-00866-y.

KIM, In Soo - JO, Eun-Kyoung. Inosine: A bioactive metabolite with multimodal actions in human diseases. In FRONTIERS IN PHARMACOLOGY, 2022, vol. 13, no., pp. Dostupné na: https://doi.org/10.3389/fphar.2022.1043970.

SHAO, Rongxue - ZHANG, Liang - YANG, Hejie - WANG, Yanbin - ZHANG, Zhijing - YUE, Jun - CHEN, Yipeng - PAN, Hao - ZHOU, Hui - QUAN, Renfu. Autophagy activation promotes the effect of iPSCs-derived NSCs on bladder function restoration after spinal cord injury. In TISSUE & CELL. ISSN 0040-8166, 2021, vol. 72, no., pp.

SOARES DOS SANTOS CARDOSO, Fellipe - BLANCO MARTINEZ, Ana Maria - MARTINS DE ALMEIDA, Fernanda. Inosine: a novel treatment for sciatic nerve injury. In NEURAL REGENERATION RESEARCH. ISSN 1673-5374, 2021, vol. 16, no. 1, pp. 127-128.

FUJII, Tsuguru - KAKINO, Kohei - TANAKA, Miyu - LEE, Jae Man - KUSAKABE, Takahiro - BANNO, Yutaka. A defect in purine nucleotide metabolism in the silkworm, Bombyx mori, causes a translucent larval integument and male infertility. In INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY. ISSN 0965-1748, 2020, vol. 126, no., pp.

TEIXEIRA, Fernanda Cardoso - GUTIERRES, Jessie Martins - SOARES, Mayara Sandrielly Pereira - DA SIVEIRA DE MATTOS, Bruna - SPOHR, Luiza - DO COUTO, Carlus Augustu Tavares - BONA, Natalia Pontes - ASSMANN, Charles Elias - MORSCH, Vera Maria - DA CRUZ, Ivana Beatrice Manica - STEFANELLO, Francieli Moro - SPANEVELLO, Roselia Maria. Inosine protects against impairment of memory induced by experimental model of Alzheimer disease: a nucleoside with multitarget brain actions. In PSYCHOPHARMACOLOGY. ISSN 0033-3158, 2020, vol. 237, no. 3, pp. 811-823.

DOS SANTOS CARDOSO, Fellipe Soares - CARDOSO, Ricardo - RAMALHO, Bruna dos Santos - TABOADA, Tiago Bastos - DOS SANTOS NOGUEIRA, Ana Carolina - BLANCO MARTINEZ, Ana Maria - DE ALMEIDA, Fernanda Martins. Inosine Accelerates the Regeneration and Anticipates the Functional Recovery after Sciatic Nerve Crush Injury in Mice. In NEUROSCIENCE. ISSN 0306-4522, 2019, vol. 423, no., pp. 206-215.

DOYLE, Claire - CRISTOFARO, Vivian - SULLIVAN, Maryrose P. - ADAM, Rosalyn M. Inosine a Multifunctional Treatment for Complications of Neurologic Injury. In CELLULAR PHYSIOLOGY AND BIOCHEMISTRY. ISSN 1015-8987, 2018, vol. 49, no. 6, pp. 2293-2303.

SANTAMARIA, Andrea J. - GUEST, James D. The current status of neuroprotection for spinal cord injury. In Neurological Aspects of Spinal Cord Injury, 2017-06-06, pp. 529-583.

ZENG, F-S - ZHANG, L. - CUI, B-J - HUANG, L-G - ZHANG, Q. - SUN, M. - LIU, B-L - MENG, F. - LI, Q. - WANG, D-Q - SUN, Q-S. Expression of autophagy in different stages of neurogenic bladder after spinal cord injury in rats. In SPINAL CORD. ISSN 1362-4393, 2017, vol. 55, no. 9, pp. 834-839.

CHUNG, Yeun Goo - SETH, Abhishek - DOYLE, Claire - FRANCK, Debra - KIM, Daniel - CRISTOFARO, Vivian - BENOWITZ, Larry I. - TU, Duong D. - ESTRADA, Carlos R. - MAUNEY, Joshua R. - SULLIVAN, Maryrose P. - ADAM, Rosalyn M. Inosine Improves Neurogenic Detrusor Overactivity following Spinal Cord Injury. In PLOS ONE. ISSN 1932-6203, 2015, vol. 10, no. 11, pp.