Study of bilateral elbow joint osteoarthritis treatment using conditioned medium from allogeneic adipose tissue-derived MSCs in Labrador retrievers

JUNUZOVIC, Maid - TROILLET, Antonia - BURK, Janina. Multiple strategies, one mission: mesenchymal stromal cell-based mechanisms of action in osteoarthritis. In FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2026, vol. 14, no., pp. ISSN 2296-634X. Dostupné na: https://doi.org/10.3389/fcell.2026.1763344.

AERI, Ananya - GORLA, Madhavi - SHARMA, G. Taru. Veterinary Regenerative Medicine: The Evolving Role of Stem Cell-Based Therapies. In Stem Cell Reviews and Reports, 2025-11-01, 21, 8, pp. 2484-2510. ISSN 26293269. Dostupné na: https://doi.org/10.1007/s12015-025-10963-z.

ALMENDROS, Angel - NEKOUEI, Omid - MOORES, Claudia - JESKY, Robert - BAIKER, Kerstin - TSE, May. Case Report: Xenogeneic mesenchymal stem cell secretome for the treatment of feline chronic gingivostomatitis. In Frontiers in Veterinary Science, 2025-01-01, 12, pp. Dostupné na: https://doi.org/10.3389/fvets.2025.1603383.

BANU, S. Amitha - MAMACHAN, Merlin - EL-HUSSEINY, Hussein M. - GOLCHIN, Ali - SHARUN, Khan. Mesenchymal stem cell therapy in veterinary orthopaedics: Evidence from canine clinical medicine. In VETERINARY RESEARCH COMMUNICATIONS, 2025, vol. 49, no. 5, pp. ISSN 0165-7380. Dostupné na: https://doi.org/10.1007/s11259-025-10843-4.

BANU, S. Amitha - SHARUN, Khan - EMMANUEL, Rony S. - MAMACHAN, Merlin - MANJUSHA, K. M. - MUTHU, Sathish - EL-HUSSEINY, Hussein M. - KUMAR, Rohit - PAWDE, Abhijit M. - DHAMA, Kuldeep - AMARPAL. Stem Cell Exosomes for Osteoarthritis in Veterinary Medicine. In Stem Cells International, 2025-01-01, 2025, 1, pp. Dostupné na: https://doi.org/10.1155/sci/4888569.

BERNI, Priscilla - DEL BUE, Maurizio - CONTI, Virna - ANDREOLI, Valentina - RAMONI, Roberto - ANGELONE, Mario - SQUASSINO, Gian Paolo - BARI, Elia - TORRE, Maria Luisa - RINALDI, Maurizio - DOTTI, Silvia - ROSSI, Rossana - YUSUF, Ishak - MAURI, Pierluigi - DI SILVESTRE, Dario - GROLLI, Stefano. Clinical evaluation of freeze-dried secretome (lyosecretome) for osteoarthritis: a controlled trial in dogs and preliminary safety assessment in horses. In International Journal of Pharmaceutics, 2025-08-20, 681, pp. ISSN 03785173. Dostupné na: https://doi.org/10.1016/j.ijpharm.2025.125864.

CARDONA-RAMIREZ, Sebastian - WOLFE, Preston N. - CORREA-VALENCIA, Nathalia M. Intra-articular use of platelet-rich plasma and its derivatives in canine osteoarthritis: a systematic review. In JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 2025, vol. 263, no. 11, pp. 1434-1443. ISSN 0003-1488. Dostupné na: https://doi.org/10.2460/javma.25.01.0033.

CHAE, Chang Woo - KIM, Dae Hyun - JO, Hyo Youn - OH, Yeon Ju - LEE, Hyun Jik. Exosomes-based applications in companion animals: Diagnostics and therapeutics in dogs and cats. In Journal of Drug Delivery Science and Technology, 2025-06-01, 108, pp. ISSN 17732247. Dostupné na: https://doi.org/10.1016/j.jddst.2025.106958.

DAVIS, Kennedy Michele - HAMILTON, Megan - MUATHE, Donald - WILDEY, Aldyn - HARRINGTON, Stephen - BITTEL, Douglas C. - FILLA, Michael - STEHNO-BITTEL, Lisa. Combination Hyaluronic Acid and Multipotent Stromal Cells Fails to Improve Rat Knee OA Outcomes Compared to Cells Alone. In Orthopedic Research and Reviews, 2025-01-01, 17, pp. 299-312. Dostupné na: https://doi.org/10.2147/ORR.S525292.

GABAI, Vladimir - BAKIN, Evgeny - LANGS, Maxim - DEVLIN, Robert - KRASNY, Sergei - BARANOU, Yauheni - POLYAKOV, Sergey - PATAPOVICH, Maksim - GVOZDEV, Sergey - KARDASH, Maksim - BAZYLEUSKI, Aliaksei - YELISEYEU, Andrei - LELIKOV, Egor - BORODKO, Andrei - SHNEIDER, Alexander. Efficacy of P62-expressing plasmid in treatment of canine osteoarthritis pain: a pilot study. In Frontiers in Veterinary Science, 2025-01-01, 12, pp. Dostupné na: https://doi.org/10.3389/fvets.2025.1519881.

GENG, Hanbo - JIN, Keyu - ZHANG, Zhaoze - ZHAO, Minwei. Progress in the study of the role of mesenchymal stem cells from different sources in osteoarthritis. In Chinese Journal of Orthopaedics, 2025-02-16, 45, 4, pp. 253-260. ISSN 02532352. Dostupné na: https://doi.org/10.3760/cma.j.cn121113-20241030-00603.

GUGJOO, Mudasir Bashir. Stem Cell-Based Regenerative Medicine in Canine Practice. In Stem Cell Based Regenerative Medicine in Canine Practice, 2025-01-01, pp. 1-553. ISBN [9781394253258, 9781394253289]. Dostupné na: https://doi.org/10.1002/9781394253289.

KONG, Hui - ZHENG, Jiale - HAN, Juanjuan - MENG, Xin - LI, Xinran - WANG, Xiaodong - ZHANG, Xin-an. The crosstalk among macrophages, chondrocytes and mesenchymal stem cells in osteoarthritis: the role of extracellular vesicles. In STEM CELL RESEARCH & THERAPY, 2025, vol. 16, no. 1, pp. Dostupné na: https://doi.org/10.1186/s13287-025-04659-x.

ZHANG, Di - YAN, Hebin - XU, Lili - ZHOU, Lisheng - LIU, Zhen - SUN, Weili - ZHAO, Haiping. Reviews of Mesenchymal Stem Cells and Secretions in the Treatment of Pet Nutritional and Metabolic Diseases. In Journal of Economic Animal, 2025-01-01, 29, 2, pp. 97-102. ISSN 10077448. Dostupné na: https://doi.org/10.13326/j.jea.2025.2043.

AN, Xingyan - WANG, Jiao - XU, Ke - ZHAO, Robert Chunhua - SU, Jiacan. Perspectives on Osteoarthritis Treatment with Mesenchymal Stem Cells and Radix Achyranthis Bidentatae. In Aging and Disease, 2024-06-01, 15, 3, pp. 1029-1045. Dostupné na: https://doi.org/10.14336/AD.2023.0817.

BERGSTRÖM, Annika - KJÖRK GRANSTRÖM, Miriam - ROEPSTORFF, Lars - ALIPOUR, Mohammad J. - PETTERSSON, Kjerstin - LJUNGVALL, Ingrid. Long-Term Effect of Intra-Articular Adipose-Derived Stromal Vascular Fraction and Platelet-Rich Plasma in Dogs with Elbow Joint Disease—A Pilot Study. In Veterinary Sciences, 2024-07-01, 11, 7, pp. Dostupné na: https://doi.org/10.3390/vetsci11070296.

CHEN, Ye - CHENG, Rui Juan - WU, Yinlan - HUANG, Deying - LI, Yanhong - LIU, Yi. Advances in Stem Cell-Based Therapies in the Treatment of Osteoarthritis. In International Journal of Molecular Sciences, 2024-01-01, 25, 1, pp. ISSN 16616596. Dostupné na: https://doi.org/10.3390/ijms25010394.

DE OLIVEIRA SIQUEIRA, Jackson - DE BARROS, Michele Andrade - MARTINS, João Flávio Panattoni - GUERRERA, Mariane Ubrik - DA SILVA LEITE, Caroline - FEITOSA, Matheus Cândido - DE MORAIS, Bruna Pereira - SOARES, Anísio Francisco - TEIXEIRA, Marcelo Weinstein. Clinical evaluation of allogeneic adipose tissue-derived stem cells for the treatment of osteoarthritis secondary to hip dysplasia in dogs. In Ciencia Rural, 2024-01-01, 54, 1, pp. ISSN 01038478. Dostupné na: https://doi.org/10.1590/0103-8478cr20220658.

LAZZARETTI FERNANDES, Tiago - TARABALLI, Francesca - SHAO, Zhenxing - ROESSLER, Philip P. - CARDONA-RAMÍREZ, Sebastián. Nonoperative and Operative Soft-Tissue, Cartilage, and Bony Regeneration and Orthopaedic Biologics of the Elbow and Upper Extremity: An Orthoregeneration Network Foundation Review. In Arthroscopy Journal of Arthroscopic and Related Surgery, 2024-12-01, 40, 12, pp. 2897-2909. ISSN 07498063. Dostupné na: https://doi.org/10.1016/j.arthro.2024.04.022.

LI, Haoran - LIU, Hongzheng - YAO, Quancheng - ZHANG, Ling - XING, Haiyang - WANG, Bing. Observation on the therapeutic effect of arthroscopy combined with cubital tunnel expansion and plasty in the treatment of elbow osteoarthritis with cubital tunnel syndrome. In Journal of Xinxiang Medical University, 2024-09-01, 41, 9, pp. 874-879. ISSN 10047239. Dostupné na: https://doi.org/10.7683/xxyxyxb.2024.09.013.