Biophysical characterization and anticancer activities of photosensitive phytoanthraquinones represented by hypericin and its model compounds

TOADER, Ana Maria - DASCALU, Izabella - IONITA, Gabriela - ANGELESCU, Daniel G. - ENACHE, Mirela. Encapsulation of quinizarin into cucurbit[8]uril macrocycle. In Journal of Molecular Liquids, 2025-09-15, 434, pp. ISSN 01677322. Dostupné na: https://doi.org/10.1016/j.molliq.2025.128044.

DRĂGOI, Cristina Manuela - ZANFIRESCU, Anca - DUMITRESCU, Ion Bogdan - UNGURIANU, Anca - MARGINĂ, Denisa Marilena - NICOLAE, Alina Crenguţa. An Experimental Dynamic Investigation of the Influence of Melatonin, Serotonin and Tryptophan on the Stability of the DNA Structure. In Chemistry (Switzerland), 2024-10-01, 6, 5, pp. 922-940. Dostupné na: https://doi.org/10.3390/chemistry6050054.

HUA, Yunqi - TIAN, Xiaoling - ZHANG, Xinyi - SONG, Ge - LIU, Yubo - ZHAO, Ye - GAO, Yuqian - YIN, Fangrui. Applications and challenges of photodynamic therapy in the treatment of skin malignancies. In Frontiers in Pharmacology, 2024-01-01, 15, pp. Dostupné na: https://doi.org/10.3389/fphar.2024.1476228.

LI, Xiaochen - LIU, Yilin - WU, Lili - ZHAO, Jie. Molecular Nanoarchitectonics of Natural Photosensitizers and Their Derivatives Nanostructures for Improved Photodynamic Therapy. In ChemMedChem, 2024-02-16, 19, 4, pp. ISSN 18607179. Dostupné na: https://doi.org/10.1002/cmdc.202300599.

NASIR, Abdul - REHMAN, Mujeeb Ur - KHAN, Tamreez - HUSN, Mansoor - KHAN, Manzar - KHAN, Ahmad - NUH, Abdifatah Mohamed - JIANG, Wei - FAROOQI, Hafiz Muhammad Umer - BAI, Qain. Advances in nanotechnology-assisted photodynamic therapy for neurological disorders: a comprehensive review. In Artificial Cells, Nanomedicine and Biotechnology, 2024-01-01, 52, 1, pp. 84-103. ISSN 21691401. Dostupné na: https://doi.org/10.1080/21691401.2024.2304814.

DOSTALÍKOVÁ, Lucie - HLÁSNÁ ČEPKOVÁ, Petra - JANOVSKÁ, Dagmar - SVOBODA, Pavel - JÁGR, Michal - DVOŘÁČEK, Václav - VIEHMANNOVÁ, Iva. Nutritional Evaluation of Quinoa Genetic Resources Growing in the Climatic Conditions of Central Europe. In Foods, 2023-04-01, 12, 7, pp. Dostupné na: https://doi.org/10.3390/foods12071440.

GUSMÃO, Luiza Araújo - RODERO, Camila Fernanda - PIRONI, Andressa Maria - CHORILLI, Marlus - PERUSSI, Janice Rodrigues. Hypericin supramolecular assembles: A way to increase the skin availability and photodynamic efficiency in tumor cells. In Photodiagnosis and Photodynamic Therapy, 2023-12-01, 44, pp. ISSN 15721000. Dostupné na: https://doi.org/10.1016/j.pdpdt.2023.103858.

KAPOOR, Surbhi - CHANDEL, Rajat - KAUR, Ramandeep - KUMAR, Satish - KUMAR, Raj - JANGHU, Sandeep - KAUR, Amarjeet - KUMAR, Vikas. The flower of Hypericum perforatum L.: A traditional source of bioactives for new food and pharmaceutical applications. In Biochemical Systematics and Ecology, 2023-10-01, 110, pp. ISSN 03051978. Dostupné na: https://doi.org/10.1016/j.bse.2023.104702.

MIĘDZYBRODZKA, Anna - KAWCZYK-KRUPKA, Aleksandra - AEBISHER, David - CIEŚLAR, Grzegorz - CZUBA, Zenon Paweł. Effects of hypericin-mediated photodynamic therapy on GM-CSF, MIF, VCAM-1 and ICAM-1 secretion in colorectal cancer cells in vitro. In European Journal of Clinical and Experimental Medicine, 2023-01-01, 21, 2, pp. 202-216. ISSN 25442406. Dostupné na: https://doi.org/10.15584/ejcem.2023.2.2.

MUND, Nitesh Kumar - ČELLÁROVÁ, Eva. Recent advances in the identification of biosynthetic genes and gene clusters of the polyketide-derived pathways for anthraquinone biosynthesis and biotechnological applications. In Biotechnology Advances, 2023-03-01, 63, pp. ISSN 07349750. Dostupné na: https://doi.org/10.1016/j.biotechadv.2023.108104.

NIU, Yajuan - GUO, Xiya - HAN, Wang - HAN, Xiaoyu - LI, Kaiting - TIAN, Si - ZHU, Ying - BAI, Dingqun - CHEN, Qing. A Combination of EGFR Inhibitors and AE-PDT Could Synergistically Suppress Breast Cancer Progression. In Anti-Cancer Agents in Medicinal Chemistry, 2023-01-01, 23, 19, pp. 2135-2145. ISSN 18715206. Dostupné na: https://doi.org/10.2174/1871520623666230908145748.

RAJPUT, Anshul - MANNA, Tanaya - HUSAIN, Syed Masood. Anthrol reductases: discovery, role in biosynthesis and applications in natural product syntheses. In Natural Product Reports, 2023-07-21, 40, 10, pp. 1672-1686. ISSN 02650568. Dostupné na: https://doi.org/10.1039/d3np00027c.

WU, Jing Jing - ZHANG, Jia - XIA, Cong Yuan - DING, Kang - LI, Xin Xin - PAN, Xue Ge - XU, Jie Kun - HE, Jun - ZHANG, Wei Ku. Hypericin: A natural anthraquinone as promising therapeutic agent. In Phytomedicine, 2023-03-01, 111, pp. ISSN 09447113. Dostupné na: https://doi.org/10.1016/j.phymed.2023.154654.

YANG, Ningning. Danthron (1,8-dihydroxyanthraquinone). In Encyclopedia of Toxicology, Fourth Edition: Volume 1-9, 2023-01-01, 3, pp. V3-471. Dostupné na: https://doi.org/10.1016/B978-0-12-824315-2.00882-4.

CHOUDHARY, Neeraj - COLLIGNON, Taylor E. - TEWARI, Devesh - BISHAYEE, Anupam. Hypericin and its anticancer effects: From mechanism of action to potential therapeutic application. In PHYTOMEDICINE, 2022, vol. 105, no., pp. ISSN 0944-7113. Dostupné na: https://doi.org/10.1016/j.phymed.2022.154356.

FOGLIETTA, Federica - CANAPARO, Roberto - COSSARI, Simone - PANZANELLI, Patrizia - DOSIO, Franco - SERPE, Loredana. Ultrasound Triggers Hypericin Activation Leading to Multifaceted Anticancer Activity. In PHARMACEUTICS, 2022, vol. 14, no. 5, pp. Dostupné na: https://doi.org/10.3390/pharmaceutics14051102.

KUNDEKOVA, Barbora - MACAJOVA, Mariana - META, Majlinda - CAVARGA, Ivan - HUNTOSOVA, Veronika - DATTA, Shubhashis - MISKOVSKY, Pavol - KRONEK, Juraj - BILCIK, Boris. The Japanese quail chorioallantoic membrane as a model to study an amphiphilic gradient copoly(2-oxazoline)s- based drug delivery system for photodynamic diagnosis and therapy research. In PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2022, vol. 40, no., pp. ISSN 1572-1000. Dostupné na: https://doi.org/10.1016/j.pdpdt.2022.103046.

RAJPUT, Anshul - DE, Arijit - MONDAL, Amit - DAS, Kiran - MAITY, Biswanath - HUSAIN, Syed Masood. A biocatalytic approach towards the preparation of natural deoxyanthraquinones and their impact on cellular viability. In NEW JOURNAL OF CHEMISTRY, 2022, vol. 46, no. 7, pp. 3087-3090. ISSN 1144-0546. Dostupné na: https://doi.org/10.1039/d1nj05513e.

YANG, Shuping - MA, Junting - LI, Tian - WANG, Peng - WANG, Xudan - ZHANG, Jian - NI, Yicheng - SHAO, Haibo. Radioiodinated hypericin as a tracer for detection of acute myocardial infarction: SPECT-CT imaging in a swine model. In Journal of Nuclear Cardiology, 2022-12-01, 29, 6, pp. 3432-3439. ISSN 10713581. Dostupné na: https://doi.org/10.1007/s12350-022-02933-6.

ZHANG, Yan - WANG, Lijun - LU, Liushen - LIU, Meiling - YUAN, Zhenbo - YANG, Lifeng - LIU, Changmei - HUANG, Shuping - RAO, Yijian. Highly efficient decontamination of tetracycline and pathogen by a natural product-derived Emodin/HAp photocatalyst. In CHEMOSPHERE, 2022, vol. 305, no., pp. ISSN 0045-6535. Dostupné na: https://doi.org/10.1016/j.chemosphere.2022.135401.