Mesoporous silica as a drug delivery system for naproxen: influence of surface functionalization

HAZIM, Shahd Ma’an - OMAR, Thamer Abdul Jabbar - BOONKANOKWONG, Veerakiet. Recent Advances in Porous Carriers for Drug Delivery: Materials, Loading Strategies, and Applications. In Iraqi Journal of Pharmacy, 2026-06-01, 23, 2, pp. 59-72. ISSN 16802594. Dostupné na: https://doi.org/10.33899/iraqij.p.2026.169790.1192.

ZHANG, Yixin - HAN, Xiaolu - TANG, Zhiqiang - ZHANG, Shanning - WANG, Yisen - ZHANG, Hui - LIU, Nan - WANG, Zengming - HU, Wenhao - ZHENG, Aiping. Preparation and evaluation of 3D-printed tacrolimus tablets based on mesoporous silica solubilization. In JOURNAL OF PHARMACEUTICAL SCIENCES, 2026, vol. 115, no. 6, pp. ISSN 0022-3549. Dostupné na: https://doi.org/10.1016/j.xphs.2026.104260.

AULIFA, Diah Lia - NURULAINI, Siti Nunung - AYODDUKI, Zahra Noor Silmi Hermawan - ANGGI, Joseph Fide - CHANDRA, Joshua Harry - BUDIMAN, Arif. Mesoporous Silica Nanoparticle as a Potential Nanocarrier to Improve the Effectiveness of Antiobesity Drugs. In DIABETES METABOLIC SYNDROME AND OBESITY, 2025, vol. 18, no., pp. 3751-3770. ISSN 1178-7007. Dostupné na: https://doi.org/10.2147/DMSO.S538644.

CAI, Mengyang - YANG, Pengpeng - FU, Jinqiu - CHEN, Guiyu - ZHANG, Keke. Insights into the Effect of Nanoconfinement Surface Chemistry on Celecoxib Aggregation and Dissolution by19F NMR Spectroscopy. In Crystal Growth and Design, 2025-08-20, 25, 16, pp. 6678-6685. ISSN 15287483. Dostupné na: https://doi.org/10.1021/acs.cgd.5c00656.

FATIMA, Rabia - KATIYAR, Pratima - KUSHWAHA, Kalpana. Recent advances in mesoporous silica nanoparticle: synthesis, drug loading, release mechanisms, and diverse applications. In FRONTIERS IN NANOTECHNOLOGY, 2025, vol. 7, no., pp. Dostupné na: https://doi.org/10.3389/fnano.2025.1564188.

FUNK, Nadine Lysyk - TAVANIELLO, Flavia Carvalho - DOS SANTOS, Juliana - BENVENUTTI, Edilson Valmir - BUCHNER, Silvio - PAESE, Karina - DEON, Monique - BECK, Ruy Carlos Ruver. Naproxen-loaded mesoporous silica nanoparticles: How can the process of incorporation affect drug placement, drug release and the in vitro naproxen irritant potential? In MICROPOROUS AND MESOPOROUS MATERIALS, 2025, vol. 384, no., pp. ISSN 1387-1811. Dostupné na: https://doi.org/10.1016/j.micromeso.2024.113458.

GORAI, Twinkle - THANASEKAR, Chandragopal - KUMAR, Pawan - BABU, Athira - KURUNGOT, Sreekumar - VINOD, C. P. A Tunable, Amine-Functionalized Porous Silica Catalyst for CO2 Transformation into Cyclic Organic Carbonates at Atmospheric Pressure. In Chemistry A European Journal. 31, 47 (2025-08-21), pp. Dostupné na: https://doi.org/10.1002/chem.202500873. ISSN 09476539.

KOVTAREVA, Svetlana Yu. - KOPISHEV, Eldar E. - ZHANG, Hongbo - FILIPPOV, Sergey K. Exploring the physicochemical interactions and loading strategies of mesoporous silicon dioxide nanoparticles for drug delivery. In EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2025, vol. 208, no., pp. ISSN 0939-6411. Dostupné na: https://doi.org/10.1016/j.ejpb.2025.114654.

KUMAR, Sampath - MOHAN, Mothilal. BOX-BEHNKEN OPTIMIZATION OF MELOXICAM MICROCAPSULE SCAFFOLDS FOR PRECISION DRUG DELIVERY IN ARTHRITIS: ENHANCED STABILITY, EFFECTIVE STERILIZATION, AND IN VIVO THERAPEUTIC POTENTIAL. In International Journal of Applied Pharmaceutics, 2025-01-01, 17, 1, pp. 410-425. ISSN 09757058. Dostupné na: https://doi.org/10.22159/ijap.2025v17i1.52160.

SANTHAMOORTHY, Madhappan - ASAITHAMBI, Perumal - RAMKUMAR, Vanaraj - ELANGOVAN, Natarajan - PERUMAL, Ilaiyaraja - KIM, Seong Cheol. A Review on the Recent Advancements of Polymer-Modified Mesoporous Silica Nanoparticles for Drug Delivery Under Stimuli-Trigger. In POLYMERS, 2025, vol. 17, no. 12, pp. Dostupné na: https://doi.org/10.3390/polym17121640.

SOBORNOVA, Valentina V. - MULLOYAROVA, Valeriya V. - BELOV, Konstantin V. - DYSHIN, Alexey A. - TOLSTOY, Peter M. - KISELEV, Michael G. - KHODOV, Ilya A. Structural and Sorption Characteristics of Nanocellulose Aerogel-Based Composite Materials Doped with Mefenamic and Flufenamic Acids: Insights from Magic Angle Spinning and High-Pressure NMR Spectroscopy. In Journal of Physical Chemistry Letters, 2025-07-03, 16, 26, pp. 6817-6824. Dostupné na: https://doi.org/10.1021/acs.jpclett.5c01303.

CHERNIIENKO, Alina - LESYK, Roman - ZAPRUTKO, Lucjusz - PAWEŁCZYK, Anna. IR-EcoSpectra: Exploring sustainable ex situ and in situ FTIR applications for green chemical and pharmaceutical analysis. In Journal of Pharmaceutical Analysis, 2024-09-01, 14, 9, pp. ISSN 20951779. Dostupné na: https://doi.org/10.1016/j.jpha.2024.02.005.

LI, Senlin - ZHENG, Yifan - ZHANG, Zhihao - XU, Shengao - PU, Yuan - WANG, Dan. Supercritical carbon dioxide as solvent for manufacturing of ibuprofen loaded gelatine sponges with enhanced performance. In Chemical Engineering and Processing Process Intensification, 2024-11-01, 205, pp. ISSN 02552701. Dostupné na: https://doi.org/10.1016/j.cep.2024.110038.

PETRIȘOR, Gabriela - MOTELICA, Ludmila - TRUȘCǍ, Roxana Doina - MȊRȚ, Andreea Luiza - VASILIEVICI, Gabriel - TOMESCU, Justinian Andrei - MANEA, Cristina - DUMBRAVǍ, Andreea Ștefania - CORBU, Viorica Maria - GHEORGHE-BARBU, Irina - FICAI, Denisa - OPREA, Ovidiu Cristian - VASILE, Bogdan Ștefan - FICAI, Anton - RAICIU, Anca Daniela. The Antimicrobial Potency of Mesoporous Silica Nanoparticles Loaded with Melissa officinalis Extract. In Pharmaceutics, 2024-04-01, 16, 4, pp. Dostupné na: https://doi.org/10.3390/pharmaceutics16040525.

PREDARSKA, Ivana - KALUĐEROVIĆ, Goran N. - HEY-HAWKINS, Evamarie. Nanostructured mesoporous silica carriers for platinum-based conjugates with anti-inflammatory agents. In Biomaterials Advances, 2024-12-01, 165, pp. Dostupné na: https://doi.org/10.1016/j.bioadv.2024.213998.

SUMBE, Rajashri B. - RAUT, Kunal G. - GAWADE, Ashwini R. - BANKAR, Amruta A. - AUTADE, Kalyani A. - KOTHAWADE, Sachin N. Synthesis of mesoporous silica nanoparticles. In Mesoporous Silica Nanoparticles: Drug Delivery, Catalysis and Sensing Applications, 2024-11-18, pp. 23-54. Dostupné na: https://doi.org/10.1515/9783111338477-002.

WÓJCIK-PASTUSZKA, Dorota - STAWICKA, Karolina - MUSIAŁ, Witold. Biopolymer-Based Hydrogel Incorporated with Naproxen Sodium and Lidocaine Hydrochloride for Controlled Drug Delivery. In Polymers, 2024-05-01, 16, 10, pp. Dostupné na: https://doi.org/10.3390/polym16101353.

GONZÁLEZ, Juan - PÉREZ, Eduardo - PEPCZYNSKA, Marzena - CALVO, Lourdes - CABAÑAS, Albertina. Supercritical Solution Impregnation of naproxen into mesoporous SiOinf2/inf SBA-15. In Journal of CO2 Utilization, 2023-07-01, 73, pp. ISSN 22129820. Dostupné na: https://doi.org/10.1016/j.jcou.2023.102518.

MINECKA, Aldona - TARNACKA, Magdalena - JURKIEWICZ, Karolina - ŻAKOWIECKI, Daniel - KAMIŃSKI, Kamil - KAMIŃSKA, Ewa. Mesoporous Matrices as a Promising New Generation of Carriers for Multipolymorphic Active Pharmaceutical Ingredient Aripiprazole. In Molecular Pharmaceutics, 2023-11-06, 20, 11, pp. 5655-5667. ISSN 15438384. Dostupné na: https://doi.org/10.1021/acs.molpharmaceut.3c00524.

WANG, Qingshuang - CUI, Yurui - AI, Wei - LI, Siqi - ZHANG, Zhe - FENG, Xiangru. Mesoporous silica SBA-15 composite for the delivery of amoxicillin against S. aureus skin infection. In New Journal of Chemistry, 2023-03-22, 47, 16, pp. 7648-7654. ISSN 11440546. Dostupné na: https://doi.org/10.1039/d3nj00109a.