Molecular mechanisms of antiproliferative effects of natural chalcones

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EL-DAKROURY, Walaa A. - ZEWAIL, Moataz B. - MANSOUR, Mai A. - MOHAMMED, Osama A. - DOGHISH, Ahmed S. - SENBEL, Ahmed - SALLAM, Al-Aliaa M. - GEBRIL, Mostafa I. - ABOUZID, Khaled A. M. - NOSHY, Mina - NOMIER, Yousra A. - ORABY, Mamdouh A. A novel furo[2,3-.d]pyrimidine-based chalcone derivative (MMK-1931) loaded chitosomes as a potential cancer therapy in an Ehrlich ascites tumour model. In JOURNAL OF DRUG TARGETING, 2025, vol. 33, no. 10, pp. 1914-1931. ISSN 1061-186X. Dostupné na: https://doi.org/10.1080/1061186X.2025.2530651.

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GUMMAGOL, Neelamma B. - YARAGUPPI, Deepak A. - PATIL, Santosh B. - PATIL, Parutagouda Shankaragouda - PATIL, Ninganagouda R. - AYACHIT, Narasimha H. Exploring the anticancer potential of novel chalcone derivatives: Synthesis, characterization, computational analysis, and biological evaluation against breast cancer. ournal of Molecular Structure [textový dokument (print)] [elektronický dokument] . – Amsterdam (Holandsko) : Elsevier. – ISSN 0022-2860. – ISSN (online) 1872-8014. – Roč. 1320 (2025), art. no. 139586. Dostupné na: https://doi.org/10.1016/j.molstruc.2024.139586.

HERMENEGILDO, Aline Mol - NAKAO, Izadora Amaral - VAZ, Luana Beatriz Araujo - COUTINHO, Gabrielly Guimaraes - TOLEDO, Joao Lucas Moraes - ALMEIDA, Tamires Cunha - AMPARO, Tatiane Roquete - ANUNCIACAO, Kamila de Fatima - SILVA, Glenda Nicioli da - BRANDAO, Geraldo Celio - BRAGA, Saulo Fehelberg Pinto - DE SOUZA, Thiago Belarmino. Design and Synthesis of Novel Chalcone Derivatives Targeting Bladder and Liver Cancer: Cytotoxicity Evaluation and Preliminary Mechanistic Studies. In ACS OMEGA, 2025, vol. 10, no. 49, pp. 60612-60626. ISSN 2470-1343. Dostupné na: https://doi.org/10.1021/acsomega.5c08480.

KILICCIOGLU, Ilker - DULGER, Gorkem - MUSATAT, Ahmad Badreddin - ATAHAN, Alparslan - CALISKAN, Emel - ALPAY, Merve - ZENGIN, Mustafa - DULGER, Basaran. Evaluation of Benzothiazole-Chalcone Hybrids: Apoptosis Induction, Docking Analysis, and Anticancer Potential in Gastric Cancer Cells. In APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2025, vol. 197, no. 10, pp. 6871-6903. ISSN 0273-2289. Dostupné na: https://doi.org/10.1007/s12010-025-05360-8.

LAICHE, Mouna Hind - BARLOW, James W. Recent Advances in the Synthesis and Biological Applications of Prenylated Chalcones. In INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2025, vol. 26, no. 20, pp. ISSN 1661-6596. Dostupné na: https://doi.org/10.3390/ijms26209845.

MARULKAR, Vinayak S. - BHATIA, Neela M. Chalcone and derived natural products: versatile scaffolds for multiple targets in treatment of Type 2 diabetes. Phytochemistry Reviews [textový dokument (print)] [elektronický dokument] : Fundamentals and Perspectives of Natural Products Research. – Amsterdam (Holandsko) : Elsevier. – ISSN 1568-7767. – ISSN (online) 1572-980X. – Roč. 24, č. 4 (2025), s. 2869-2906 Dostupné na: https://doi.org/10.1007/s11101-024-10007-3.

MUSATAT, Ahmad Badreddin - KILICCIOGLU, Ilker - LOUAILECHE, Tinhinane - DULGER, Gorkem - MAOUCHE, Chaima - TABTI, Salima - KURMAN, Yener - ATAHAN, Alparslan. Synergistic fusion of carbazole, quinoline, and chalcone scaffolds: A computational and experimental exploration of hybrid compounds as selective anticancer agents. In JOURNAL OF MOLECULAR STRUCTURE, 2025, vol. 1348, no., pp. ISSN 0022-2860. Dostupné na: https://doi.org/10.1016/j.molstruc.2025.143401.

NIKOLIC, Ivana - LUKOVIC, Jovan - MARKOVIC, Tijana - RISTIC, Tijana - BULIC, Marija - ANDELKOVIC, Marija - SORAK, Marija - MILINKOVIC, Milica - MUSKINJA, Jovana - CANOVIC, Petar - MITROVIC, Marina. New O-alkyl Chalcone Derivative Exhibits Antiproliferative Potential in Colorectal and Cervical Cancer Cells by Inducing G0/G1 Cell Cycle Arrest and Mitochondrial-mediated Apoptosis. In CURRENT MEDICINAL CHEMISTRY, 2025, vol. 32, no. 36, pp. 8152-8170. ISSN 0929-8673. Dostupné na: https://doi.org/10.2174/0109298673317485240827093121.

WANG, Yu-Qiong - LUO, Li-Long - CHEN, Li-Ming - GOU, Chang-Long. Biovalorization of Astragalus membranaceus var. mongholicus Stems by White Rot Fungi Under Solid-State Fermentation as Ruminant Feed. In AGRONOMY-BASEL, 2025, vol. 15, no. 3, pp. Dostupné na: https://doi.org/10.3390/agronomy15030650.

ZIQUBU, Khanyisani - MAZIBUKO-MBEJE, Sithandiwe E. - DLUDLA, Phiwayinkosi. Regulation of adipokine and batokine secretion by dietary flavonoids, as a prospective therapeutic approach for obesity and its metabolic complications. In BIOCHIMIE, 2025, vol. 230, no., pp. 95-113. ISSN 0300-9084. Dostupné na: https://doi.org/10.1016/j.biochi.2024.11.007.