ADC Immunohistochemical Evidence for the Presence of Synaptic Connections of Nitrergic Neurons in the Rat Rostral Migratory Stream / Blaško Juraj, Fabianová Kamila, Martončíková Marcela, Sopková Drahomíra, Račeková Enikö, 2013. In: Cellular and Molecular Neurobiology. - ISSN 0272-4340. - Vol. 33, č. 6(2013), s. 753 - 757.
| Basic data | |
|---|---|
| OCA1. Surname awarded to the assessed person | Sopková |
| OCA2. Name awarded to the assessed person | Drahomíra |
| OCA3. Degrees awarded to the assessed person | Assoc. prof. , DVM, PhD |
| OCA4. Hyperlink to the entry of the person in the Register of university staff | https://www.portalvs.sk/regzam/detail/6022 |
| OCA5. Area of assessment | study programme man-animal relationship and its use in canistherapy and hipotherapy · I. degree |
| OCA6. Category of the research/artistic/other output | scientific output |
| OCA7. Year of publication of the research/artistic/other output | 2013 |
| OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA) | UVL.Košice.0018005 |
| OCA9. Hyperlink to the record in CRPA or CRAA | http://www.crepc.sk/portal?fn=*recview&uid=1077853&pageId=resultform&full=0 |
| Characteristics of the output that is not registered in CRPA or CRAA | |
| OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs | https://www.webofscience.com/wos/woscc/full-record/WOS:000322256100002 |
| OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs | ADC Immunohistochemical Evidence for the Presence of Synaptic Connections of Nitrergic Neurons in the Rat Rostral Migratory Stream / Blaško Juraj, Fabianová Kamila, Martončíková Marcela, Sopková Drahomíra, Račeková Enikö, 2013. In: Cellular and Molecular Neurobiology. - ISSN 0272-4340. - Vol. 33, č. 6(2013), s. 753 - 757. |
| OCA12. Type of the output (if the output is not registered in CRPA or CRAA) | article |
| OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.) | https://link.springer.com/content/pdf/10.1007/s10571-013-9956-1.pdf |
| OCA14. Characteristics of the author's contribution | |
| OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc. | |
| Other data | |
| OCA16. Annotation of the output in English | The rostral migratory stream (RMS) is a migration route for neuroblasts originating in the richest neurogenic niche of the adult mammalian brain—the subventricular zone. Most studies are focused on cellular dynamics of migrating neuroblasts and interactions between neuroblasts and astrocytes which both represent the major cellular component of the RMS. Our previous experiments have brought evidence about the existence of a small population of mature neurons in the adult rat RMS with capacity to produce nitric oxide (NO). In order to further support functional significance of nitrergic cells, the aim of the present study was to determine whether NO producing neurons could form synapses. Sagittal sections from the adult rat brain were processed for simultaneous immunohistochemical detection of neuronal nitric oxide synthase (nNOS), the enzyme present in NO producing cells and synaptophysin, a glycoprotein found in synaptic vesicles. Synaptophysin positivity in the RMS was significantly lower in comparison with other brain areas, but its colocalization with nNOS-positive neurons was obvious. Our results suggest that nitrergic neurons in the RMS could be involved in a neuronal circuitry with potential impact on regulation of neurogenesis in the RMS. |
| OCA17. List of maximum 5 most significant citations corresponding to the output | Larriva-Sahd, J., León-Olea, M., Vargas-Barroso, V., Varela-Echavarría, A., Concha, L.On the existence of mechanoreceptors within the neurovascular unit of the mammalian brain(2019) Brain Structure and Function, 224 (6), pp. 2247-2267 Shefa, U., Kim, D., Kim, M.-S., Jeong, N.Y., Jung, J.Roles of Gasotransmitters in Synaptic Plasticity and Neuropsychiatric Conditions(2018) Neural Plasticity, 2018, art. no. 1824713 3. Hanics, J., Szodorai, E., Tortoriello, G., Malenczyk, K., Keimpema, E., Lubec, G., Hevesi, Z., Lutz, M.I., Kozsurek, M., Puskár, Z., Tóth, Z.E., Wagner, L., Kovács, G.G., Hökfelt, T.G.M., Harkany, T., Alpár, A.Secretagogin-dependent matrix metalloprotease-2 release from neurons regulates neuroblast migration(2017) Proceedings of the National Academy of Sciences of the United States of America, 114 (10), pp. E2006-E2015 Nasyrova, R.F., Ivashchenko, D.V., Ivanov, M.V., Neznanov, N.G.Role of nitric oxide and related molecules in schizophrenia pathogenesis: Biochemical, genetic and clinical aspects(2015) Frontiers in Physiology, 6 (MAY), art. no. 139 Larriva-Sahd, J.Structural variation and interactions among astrocytes of the rostral migratory stream and olfactory bulb: II. Golgi and electron microscopic study of the adult rat(2014) Neuroscience Research, 89, pp. 10-30 |
| OCA18. Characteristics of the output's impact on socio-economic practice | |
| OCA19. Characteristics of the output and related activities' impact on the educational process | |