| OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs | ADC Effects of orally administered beta-1,3/1,6-glucan on vaccination responses and immunological parameters in dogs = Vplyv orálne podávaného beta-1,3/1,6-glukánu na vakcinačnú odpoveď a imunologické parametre in dogs / Vojtek Boris, Mojžišová Jana, Smrč Peter, Drážovská Monika, 2017. In: Food and Agricultural Immunology. - ISSN 0954-0105. - Vol. 28, č. 6(2017), s. 993-1002. |
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| OCA16. Annotation of the output in English | The aim of this study was to evaluate immunomodulatory effects of orally administered beta-1,3/1,6-glucan on leukocyte functions and vaccination responses in dogs. Thirty puppies were divided into two groups (G and C) of 15 individuals each and vaccinated against rabies and canine parvovirus-2. Dogs from the group G were orally administered 4 mg/kg soluble glucans once daily for 98 days. The phagocytic and metabolic activity of leukocytes and proliferation activity of lymphocytes were evaluated on days 0, 14, 28, 42 and 56. The antibody response to canine parvovirus type 2 and rabies virus were measured weekly. Comparing both groups, we noticed a significant increase in phagocytic activity of leukocytes (p < .001). Protective levels of antibodies against rabies virus, as well as against CPV-2 were reached earlier in the glucan treated group G. Our results suggest positive effects of glucan on some nonspecific immunity parameters, as well as on evaluated vaccination response. |
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| OCA17. List of maximum 5 most significant citations corresponding to the output | Byrne, J., Knobel, D., Moore, S.M., Gatrell, S., Butaye, P. The influence of β-1,3-1,6-glucans on rabies vaccination titers in cats(2020) Veterinary Sciences, 7 (3), art. no. 118, .
Scariot, D.B., Volpato, H., Fernandes, N.S., Lazarin-Bidóia, D., Borges, O., Sousa, M.C., Rosa, F.A., Jacomini, A.P., Silva, S.O., Ueda-Nakamura, T., Rubira, A.F., Nakamura, C.V. Oral treatment with T6-loaded yeast cell wall particles reduces the parasitemia in murine visceral leishmaniasis model(2019) Scientific Reports, 9 (1), art. no. 20080
Wojcik, A., Zietek, J., Winiarczyk, S. Canine parvovirosis: Still an existing problem [Parwowiroza psow-problem wciqz aktualny](2019) Medycyna Weterynaryjna, 75 (8), pp. 472-479
van Hamme, V., Spaepen, R., Smeets, N. Algal beta-(1,3)-glucan and its effect on infectious bursal disease vaccination in poultry [Beta-(1,3)-glucanen uit algen en hun effect op vaccinatie tegen infectieuze bursitis bij pluimvee](2019) Vlaams Diergeneeskundig Tijdschrift, 88 (6), pp. 313-315
. Vetvicka, V., Fernandez-Botran, R. β-Glucan and parasites(2018) Helminthologia (Poland), 55 (3), pp. 177-184. |
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