ADC : Effect of pyrethroids on female genital system. Review / Marettová Elena, Maretta Milan, Legáth Jaroslav, 2017. In: Animal Reproduction Science. - ISSN 0378-4320.

ADC : Effect of pyrethroids on female genital system. Review / Marettová Elena, Maretta Milan, Legáth Jaroslav, 2017. In: Animal Reproduction Science. - ISSN 0378-4320. - Vol. 184(2017), s. 132-138.

Basic data
OCA1. Surname awarded to the assessed person	Legáth
OCA2. Name awarded to the assessed person	Jaroslav
OCA3. Degrees awarded to the assessed person	Prof. , DVM, CSc.
OCA4. Hyperlink to the entry of the person in the Register of university staff	https://www.portalvs.sk/regzam/detail/2269
OCA5. Area of assessment	study programme animal hygiene and environment · III. degree
OCA6. Category of the research/artistic/other output	scientific output
OCA7. Year of publication of the research/artistic/other output	2017
OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA)	UVL.Košice.0028750
OCA9. Hyperlink to the record in CRPA or CRAA	http://www.crepc.sk/portal?fn=*recview&uid=2207159&pageId=resultform&full=0
Characteristics of the output that is not registered in CRPA or CRAA
OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs	https://www.webofscience.com/wos/woscc/full-record/WOS:000411300700015
OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs	ADC : Effect of pyrethroids on female genital system. Review / Marettová Elena, Maretta Milan, Legáth Jaroslav, 2017. In: Animal Reproduction Science. - ISSN 0378-4320. - Vol. 184(2017), s. 132-138.
OCA12. Type of the output (if the output is not registered in CRPA or CRAA)	article
OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.)	https://pubmed.ncbi.nlm.nih.gov/28735887
OCA14. Characteristics of the author's contribution	Coordinator of the scientific team
OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc.
Other data
OCA16. Annotation of the output in English	Pyrethroids have been associated with a range of toxicological effects on various organs in animals.Recent animal studies suggest that neurodevelopmental, reproductive, and immunological effects may result following exposure to some pyrethroids at levels below those that induce overt signs of neurotoxicity. A variety of pyrethroids and their metabolites have the potential to affect the reproductive system. Dose-dependent effects on reproduction are associated with exposure across pyrethroid types. In mammals, permethrin and tetramethrin and cypermethrin have been found to be associated with adverse effects at high doses. Fenvalerate, deltamethrin, cypermethrin, caused morphometric and structural changes in the female genital organs. These pyrethroids affect ovulation, cause atresia of follicles, decrease the number of follicular cells, oocytes and corpora lutea and induce vesicular atrophy of the endometrial glands. The potential hormonal activity of pyrethroids showed that certain pyrethroids and their metabolites have multiple effects on the endocrine system. The level of steroid hormones, such as progesterone and estradiol, was inhibited. The pyrethorids may have the potential to mimic estrogens or to inhibit estrogen action. Some metabolites of pyrethroids, in particular permethrin and cypermethrin, are more likely to interact with the cellular estrogen receptors than the parent pyrethroids. Though several pyrethroids posses low toxicity, some pyrethroids, such as deltamethrin, cypermethrin, fenvalerate and bifenthrin have showed considerable toxicity.
OCA17. List of maximum 5 most significant citations corresponding to the output	GUERREIRO, A. C. - CECATI, F. M. - ARDANÁZ, C. E. - DONADEL, O. J. - TONN, C. E. - SOSA, M. E. Assessment of the Insecticidal Potential of the Eupatorium buniifolium Essential Oil Against Triatoma infestans (Hemiptera: Reduviidae). A Chiral Recognition Approach. In Neotropical Entomology. ISSN 1519566X, 2018-06-01, 47, 3, pp. 418-428., Registrované v: Scopus GUO, Junnan - XU, Jinzhong - ZHANG, Junshi - AN, Lei. Alteration of mice cerebral cortex development after prenatal exposure to cypermethrin and deltamethrin. In Toxicology Letters. ISSN 03784274, 2018-05-01, 287, pp. 1-9., Registrované v: Scopus TIAN, Jiewei - LONG, Xiufeng - ZHANG, Shuai - QIN, Qiumian - GAN, Longzhan - TIAN, Yongqiang. Screening cyhalothrin degradation strains from locust epiphytic bacteria and studying Paracoccus acridae SCU-M53 cyhalothrin degradation process. In Environmental Science and Pollution Research. ISSN 09441344, 2018-04-01, 25, 12, pp. 11505-11515., Registrované v: Scopus ZHOU, Yong jiang - WANG, Xiao dan - XIAO, Sha - YU, De E. - WANG, Li qing - WANG, Ji hong - ZHU, Hui quan. Exposure to beta-cypermethrin impairs the reproductive function of female mice. In Regulatory Toxicology and Pharmacology. ISSN 02732300, 2018-06-01, 95, pp. 385-394., Registrované v: Scopus HUANG WEI - LI NA - XU RUIHAN - LI TING - LI CHONGYONG. Determination of nine pyrethroid pesticide residues in tea by gas chromatography-tandem mass spectrometry combined with accelerated solvent extraction and solid phase extraction. In CHINESE JOURNAL OF CHROMATOGRAPHY. ISSN 1000-8713, 2018, vol. 36, no. 12, pp. 1303-1310., Registrované v: WoS
OCA18. Characteristics of the output's impact on socio-economic practice	Pyrethroids are one of the basic insecticides in both agricultural and municipal areas. Their safe use is regulated by the assessment of their health as well as environmental risk. High doses can have a negative effect on human and animal health and a negative effect on pollinators and the environment, and knowledge of their negative effect can be used to manage their application and use.
OCA19. Characteristics of the output and related activities' impact on the educational process	The findings presented in the article are used directly in the pedagogical process, in the presentation of risk assessment and risk characteristics of pyrethroids for humans, animals and the environment.