ADC First look at the venom of Naja ashei / Hus, Konrad Kamil [Autor, 25%] ; Buczkowicz, Justyna [Autor, 10%] ; Petrilla, Vladimír [Autor, UVLFKAHF, 15%] ; Petrillová, Monika [Autor, UVLFKVVP, 10%] ; Łyskowski, Andrzej [Autor, 10%] ; Legáth, Jaroslav [Autor, UVLFKFTO, 10%] ; Bocian, Aleksandra [Autor, 20%]. – [angličtina]. – [OV 200]. – DOI 10.3390/molecules23030609. – WOS CC ; SCOPUS ; CCC In: Molecules [elektronický dokument] : a Journal of Synthetic Chemistry and Natural Product Chemistry. – Bazilej (Švajčiarsko) : Multidisciplinary Digital Publishing Institute. – ISSN (online) 1420-3049. – Roč. 23, č. 3 (2018), art. no. 609, s. [1-10] [online] . – IF: 3,060 ; SJR: 0.757 ; CiteScore: 4,1 ; SNIP: 1,217

Basic data
OCA1. Surname awarded to the assessed person	Legáth
OCA2. Name awarded to the assessed person	Jaroslav
OCA3. Degrees awarded to the assessed person	Prof. , DVM, CSc.
OCA4. Hyperlink to the entry of the person in the Register of university staff	https://www.portalvs.sk/regzam/detail/2269
OCA5. Area of assessment	study programme animal hygiene and environment · III. degree
OCA6. Category of the research/artistic/other output	scientific output
OCA7. Year of publication of the research/artistic/other output	2018
OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA)	ID = 100226
OCA9. Hyperlink to the record in CRPA or CRAA	https://app.crepc.sk/?fn=detailBiblioForm&sid=D4E1A2C7A0DFD9B774A94DD3A7
Characteristics of the output that is not registered in CRPA or CRAA
OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs	https://www.webofscience.com/wos/woscc/full-record/WOS:000428514100100
OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs	ADC First look at the venom of Naja ashei / Hus, Konrad Kamil [Autor, 25%] ; Buczkowicz, Justyna [Autor, 10%] ; Petrilla, Vladimír [Autor, UVLFKAHF, 15%] ; Petrillová, Monika [Autor, UVLFKVVP, 10%] ; Łyskowski, Andrzej [Autor, 10%] ; Legáth, Jaroslav [Autor, UVLFKFTO, 10%] ; Bocian, Aleksandra [Autor, 20%]. – [angličtina]. – [OV 200]. – DOI 10.3390/molecules23030609. – WOS CC ; SCOPUS ; CCC In: Molecules [elektronický dokument] : a Journal of Synthetic Chemistry and Natural Product Chemistry. – Bazilej (Švajčiarsko) : Multidisciplinary Digital Publishing Institute. – ISSN (online) 1420-3049. – Roč. 23, č. 3 (2018), art. no. 609, s. [1-10] [online] . – IF: 3,060 ; SJR: 0.757 ; CiteScore: 4,1 ; SNIP: 1,217
OCA12. Type of the output (if the output is not registered in CRPA or CRAA)	article
OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.)	https://pubmed.ncbi.nlm.nih.gov/29518026/
OCA14. Characteristics of the author's contribution	Coordinator of the scientific team.
OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc.	Naja ashei is an African spitting cobra species closely related to N. mossambica andN. nigricollis. It is known that the venom of N. ashei, like that of other African spitting cobras,mainly has cytotoxic effects, however data about its speciﬁc protein composition are not yet available.Thus, an attempt was made to determine the venom proteome of N. ashei with the use of 2-Delectrophoresis and MALDI ToF/ToF (Matrix-Assisted Laser Desorption/Ionization Time of Flight)mass spectrometry techniques. Our investigation revealed that the main components of analysedvenom are 3FTxs (Three-Finger Toxins) and PLA2s (Phospholipases A2). Additionally the presenceof cysteine-rich venom proteins, 50-nucleotidase and metalloproteinases has also been conﬁrmed.The most interesting fact derived from this study is that the venom of N. ashei includes proteins notdescribed previously in other African spitting cobras—cobra venom factor and venom nerve growthfactor. To our knowledge, there are currently no other reports concerning this venom compositionand we believe that our results will signiﬁcantly increase interest in research of this species.
Other data
OCA16. Annotation of the output in English	Naja ashei is an African spitting cobra species closely related to N. mossambica andN. nigricollis. It is known that the venom of N. ashei, like that of other African spitting cobras,mainly has cytotoxic effects, however data about its speciﬁc protein composition are not yet available.Thus, an attempt was made to determine the venom proteome of N. ashei with the use of 2-Delectrophoresis and MALDI ToF/ToF (Matrix-Assisted Laser Desorption/Ionization Time of Flight)mass spectrometry techniques. Our investigation revealed that the main components of analysedvenom are 3FTxs (Three-Finger Toxins) and PLA2s (Phospholipases A2). Additionally the presenceof cysteine-rich venom proteins, 50-nucleotidase and metalloproteinases has also been conﬁrmed.The most interesting fact derived from this study is that the venom of N. ashei includes proteins notdescribed previously in other African spitting cobras—cobra venom factor and venom nerve growthfactor. To our knowledge, there are currently no other reports concerning this venom compositionand we believe that our results will signiﬁcantly increase interest in research of this species.
OCA17. List of maximum 5 most significant citations corresponding to the output	Quantitative Characterization of the Hemorrhagic, Necrotic, Coagulation-Altering Properties and Edema-Forming Effects of Zebra Snake (Naja nigricincta nigricincta) Venom / Kandiwa, Erick ; Mushonga, Borden ; Samkange, ; Fabiano, Ezequiel . – DOI 10.1155/2018/6940798. – SCOPUS In: Journal of toxicology. – ISSN 16878191. – ISSN (online) 16878205. – Roč. 2018 (2018), art.no. 6940798, s. [1-8] Snake Venom Peptides: Tools of Biodiscovery / Munawar, Aisha ; Ali, Syed Abid ; Akrem, Ahmed ; Betzel, Christian [Autor]. – DOI 10.3390/toxins10110474. – WOS CC In: Toxins [elektronický dokument] : Open Access Journal of Toxinology. – Basel (Švajčiarsko) : Multidisciplinary Digital Publishing Institute. – ISSN (online) 2072-6651. – Roč. 10, č. 11 (2018), art. no. 474, s. [1-29] [online] Distinctive Distribution of Secretory Phospholipases A(2) in the Venoms of Afro-Asian Cobras (Subgenus: Naja, Afronaja, Boulengerina and Uraeus) / Tan, Choo Hock ; Wong, Kin Ying ; Tan, Nget Hong ; Ng, Tzu Shan ; Tan, Kae Yi [Autor]. – DOI 10.3390/toxins11020116. – WOS CC In: Toxins [elektronický dokument] : Open Access Journal of Toxinology. – Basel (Švajčiarsko) : Multidisciplinary Digital Publishing Institute. – ISSN (online) 2072-6651. – Roč. 11, č. 2 (2019), [online] Enzymatic activity and brine shrimp lethality of venom from the large brown spitting cobra (Naja ashei) and its neutralization by antivenom / Okumu, Mitchel Otieno ; Mbaria, James Mucunu ; Gikunju, Joseph Kangangi ; Mbuthia, Paul Gichohi ; Madadi, Vincent Odongo ; Ochola, Francis Okumu [Autor]. – DOI 10.1186/s13104-020-05167-2. – WOS CC ; SCOPUS In: BMC Research Notes [elektronický dokument] . – ISSN (online) 1756-0500. – Roč. 13, č. 1 (2020), art. no. 325 [online] Proteomic Investigations of Two Pakistani Naja Snake Venoms Species Unravel the Venom Complexity, Posttranslational Modifications, and Presence of Extracellular Vesicles / Manuwar, Aisha ; Dreyer, Benjamin ; Boehmert, Andreas ; Ullah, Anwar ; Mughal, Zia ; Akrem, Ahmed ; Ali, Syed Abid ; Schlueter, Hartmut ; Betzel, Christian . – DOI 10.3390/toxins12110669. – WOS CC In: Toxins [elektronický dokument] : Open Access Journal of Toxinology. – Basel (Švajčiarsko) : Multidisciplinary Digital Publishing Institute. – ISSN (online) 2072-6651. – Roč. 12, č. 11 (2020), [online]
OCA18. Characteristics of the output's impact on socio-economic practice	The environment, habitats in which individual snakes of the same species live significantly affects the composition of snake venom. Therefore, his study from the point of view of toxicology is very important for understanding the preparation of antivirins that would universally protect humans and animals from the effects of poison after a bite.
OCA19. Characteristics of the output and related activities' impact on the educational process	The findings presented in the article are used in the pedagogical process, in the presentation of the interaction between the environment and the animal species that live in it, respectively. on the impact of local habitats on animal behavior and their metabolic response in the form of venom production to the local conditions in which the animals live. Students are, of course, interpreted the latest results on the composition of the venom of individual species of snakes.