ADC VOJTEK, Boris [50 %] - MOJŽIŠOVÁ, Jana [10 %] - KULICHOVÁ, Lucia [5 %] - SMRČO, Peter [5 %] - DRÁŽOVSKÁ, Monika [30 %]. Effects of dietary nucleotides and cationic peptides on vaccination response in cats. In Veterinární medicína. ISSN 0375-8427, 2021, vol. 66, no. 1, p. 17-23. (2020: 0.565 - IF, 0.883 - IF 5y, 50 - H-index, 0.272 - SJR, Q3 - SJR Best Q, Q4 - JCR Best Q). Dostupné na internete: .

Basic data
OCA1. Surname awarded to the assessed person	Mojžišová Vaščinec
OCA2. Name awarded to the assessed person	Jana
OCA3. Degrees awarded to the assessed person	Dr. h. c. Prof. , DVM, PhD
OCA4. Hyperlink to the entry of the person in the Register of university staff	https://www.portalvs.sk/regzam/detail/6013
OCA5. Area of assessment	study programme infectious diseases of animals · III. degree
OCA6. Category of the research/artistic/other output	scientific output
OCA7. Year of publication of the research/artistic/other output	2021
OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA)	247276
OCA9. Hyperlink to the record in CRPA or CRAA	https://app.crepc.sk/?fn=detailBiblioFormChildM10AO&sid=CCC8921E0300D694B2B2383F3C&seo=CREP%C4%8C-detail-%C4%8Cl%C3%A1nok
Characteristics of the output that is not registered in CRPA or CRAA
OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs	https://www.webofscience.com/wos/woscc/full-record/WOS:000606544600003
OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs	ADC VOJTEK, Boris [50 %] - MOJŽIŠOVÁ, Jana [10 %] - KULICHOVÁ, Lucia [5 %] - SMRČO, Peter [5 %] - DRÁŽOVSKÁ, Monika [30 %]. Effects of dietary nucleotides and cationic peptides on vaccination response in cats. In Veterinární medicína. ISSN 0375-8427, 2021, vol. 66, no. 1, p. 17-23. (2020: 0.565 - IF, 0.883 - IF 5y, 50 - H-index, 0.272 - SJR, Q3 - SJR Best Q, Q4 - JCR Best Q). Dostupné na internete: .
OCA12. Type of the output (if the output is not registered in CRPA or CRAA)	article
OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.)	https://www.mdpi.com/2077-0472/11/8/744/htm
OCA14. Characteristics of the author's contribution	The author was the initiator of the idea to investigate the possible influence of nucleotides and cationic peptides on the reaction of cats to vaccination.
OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc.	It can be conclude that the addition of 0.5% HS to laying hen feed had a positive effect on laying rate, daily egg mass, egg weight, feed conversion, and eggshell quality and also had an immunostimulatory effect manifested by the increasing activity of the phagocytes and the B cell immune response. On the other hand, there was an observed increase in the number of enterobacteria in the intestinal contents, and the proportion of T lymphocytes in the blood was significantly reduced. The presented results confirm that HS can be used for the improvement of egg production and quality and for activation of phagocytosis and specific antibody immunity, but their influence on the intestinal microbiota will need to be further studied with respect to a wider range of microbial species inhabiting the digestive tract of laying hens.
Other data
OCA16. Annotation of the output in English	Despite the fact that humic substances (HS) have been frequently studied in relation to their effects on livestock health, studies on their influence on egg production and quality, immunity, and intestinal microbiota of laying hens are limited. In this study, the influence of 0.5% HS supplementation on the specific production parameters of eggshell mineral quality, immune parameters (relative expression of IgA, IGF-2, MUC-2 gene in cecum; activity of phagocytes, percentage of selected lymphocyte subpopulations in the peripheral blood), and number of lactic acid bacteria and enterobacteria in the intestinal contents in laying hens was tested. The addition of 0.5% HS to the laying hen feed had a positive effect on egg laying rate, daily egg mass, egg weight, feed conversion and eggshell quality and also had an immunostimulatory effect manifested by increased phagocyte activity and B cell response. Concurrently, an increase in the number of enterobacteria in the intestinal contents and a decrease in the proportion of T lymphocytes (p < 0.05) was observed, which can be considered as a negative effect of HS. The results confirmed that HS can be used for the improvement of egg production and targeted immunostimulation.
OCA17. List of maximum 5 most significant citations corresponding to the output	Karaffova, V ; Mudronova, D; Semjon, B; Klempova, T; Slany, O; Certik, M; Nagy, J ; Bartkovsky, M ; Marcincak, S. Immune Response and Fatty Acid Profile of Eggs from Laying Hens Fed Fermented Feed Rich in Polyunsaturated Fatty Acids. In FERMENTATION-BASEL, 2021, Volume8, Issue3, Article Number 98
OCA18. Characteristics of the output's impact on socio-economic practice	The possible influence of nucleotides and cationic peptides on the response of cats to vaccination is an interesting area for research and further understanding of post-vaccination reactions in animals with the aim of positively influencing them.
OCA19. Characteristics of the output and related activities' impact on the educational process	The output has a positive impact on the development of students\' cognitive abilities and their ability to use new knowledge in post-graduation practice.