ADM PETROVOVÁ, Eva - GIRETOVÁ, Mária - KVASILOVÁ, Alena - BEŇADA, Oldřich - DANKO, Ján - MEDVECKÝ, Ľubomír - SEDMERA, David. Preclinical alternative model for analysis of porous scaffold biocompatibility applicable in bone tissue engineering. In ALTEX – Alternatives to animal experimentation. ISSN 1868-596X, 2019, vol. 36, no. 1, p. 121-130. (2019: 5.787 - IF, 5.329 - IF 5y, 47 - H-index, 1.270 - SJR, Q1 - SJR Best Q, Q1

ADM PETROVOVÁ, Eva - GIRETOVÁ, Mária - KVASILOVÁ, Alena - BEŇADA, Oldřich - DANKO, Ján - MEDVECKÝ, Ľubomír - SEDMERA, David. Preclinical alternative model for analysis of porous scaffold biocompatibility applicable in bone tissue engineering. In ALTEX – Alternatives to animal experimentation. ISSN 1868-596X, 2019, vol. 36, no. 1, p. 121-130. (2019: 5.787 - IF, 5.329 - IF 5y, 47 - H-index, 1.270 - SJR, Q1 - SJR Best Q, Q1 - JCR Best Q).

Basic data
OCA1. Surname awarded to the assessed person	Petrovová
OCA2. Name awarded to the assessed person	Eva
OCA3. Degrees awarded to the assessed person	Prof. , DVM, PhD
OCA4. Hyperlink to the entry of the person in the Register of university staff	https://www.portalvs.sk/regzam/detail/6066
OCA5. Area of assessment	study programme veterinary morphology and physiology · III. degree
OCA6. Category of the research/artistic/other output	scientific output
OCA7. Year of publication of the research/artistic/other output	2019
OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA)	118028
OCA9. Hyperlink to the record in CRPA or CRAA	https://app.crepc.sk/?fn=detailBiblioFormChildIJ87D&sid=CB98FB4AD6F667254539F2265B&seo=CREP%C4%8C-detail-%C4%8Cl%C3%A1nok
Characteristics of the output that is not registered in CRPA or CRAA
OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs	https://www.webofscience.com/wos/woscc/full-record/WOS:000455105700010
OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs	ADM PETROVOVÁ, Eva - GIRETOVÁ, Mária - KVASILOVÁ, Alena - BEŇADA, Oldřich - DANKO, Ján - MEDVECKÝ, Ľubomír - SEDMERA, David. Preclinical alternative model for analysis of porous scaffold biocompatibility applicable in bone tissue engineering. In ALTEX – Alternatives to animal experimentation. ISSN 1868-596X, 2019, vol. 36, no. 1, p. 121-130. (2019: 5.787 - IF, 5.329 - IF 5y, 47 - H-index, 1.270 - SJR, Q1 - SJR Best Q, Q1 - JCR Best Q).
OCA12. Type of the output (if the output is not registered in CRPA or CRAA)	abstract
OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.)	https://www.altex.org/index.php/altex/article/view/1145
OCA14. Characteristics of the author's contribution	Concept, Formal analysis, Funding acquisition, Investigation, Methodology, Writing—original draft
OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc.	This study investigates methods to monitor angiogenesis in polyhydroxybutyrate (PHB)/chitosan-based porous biopolymer scaffolds. We used an avian chorioallantoic membrane (CAM) model to monitor the formation of new blood vessels inside the implant structure. We also characterized the chemical properties of the surface in the implant under test as well as the tissue response of the CAM.
Other data
OCA16. Annotation of the output in English	This study investigates methods for monitoring angiogenesis within porous biopolymer scaffolds on the basis of polyhydroxybutyrate (PHB)/chitosan. We use the chick and quail chorioallantoic membrane (CAM) assay as an in vivo model focused on the formation of new blood vessels inside the implant structure. Chemical properties of the surface in biopolymer scaffold matrix were characterized as well as the tissue reaction of the CAM.
OCA17. List of maximum 5 most significant citations corresponding to the output	Tao, F., Cheng, Y., Shi, X., Zheng, H., Du, Y., Xiang, W., Deng, H., 2020: Applications of chitin and chitosan nanofibers in bone regenerative engineering. Carbohydrate Polymers, 230, 115658. CC Wang, W., Jia, Q., Huang, H., Li, X., Zeng, H., Ding, W., Witte, F., Zhang, C., Jia, W., Yuan, G., 2020: The in vitro and in vivo biological effects and osteogenic activity of novel biodegradable porous Mg alloy scaffolds. Materials and Design, 189, 108514. CC Wan, Q.-Q., Qin, W.-P., Shen, M.-J., Li, B., Liu, S.-Y., Tay, F.R., Jiao, K., Niu, L.-N., 2020: Simultaneousregeneration of bone and nerves through materials and architectural design: Are we there yet? Advanced Functional Materials, 30 (48), 2003542 CC Childs, P.G., Reid, S., Salmeron-Sanchez, M., Dalby, M.J., 2020: Hurdles to uptake of mesenchymal stem cells and their progenitors in therapeutic products. Biochemical Journal, 477 (17), 3349-3366. CC Shamim, S., Zameer, P., Qayyum, Z., Ali, M.A., Chotana, G.A., Lodhi, R.N., Khan, M.A., Batool, F., Khan, M., Ashraf, M., Malik, A., 2020: Corncob; the Inducer of Polyhydroxybutyrates (PHBs) of Bacillus licheniformis-MK656314. International Journal of Agriculture and Biology, 24 (1), 35-42. 34. Petrovova, E., Giretova, M., Kvasilova, A., Benada, O., Danko, J., Medvecky, L., Sedmera, D., 2019: Preclinical alternative model for analysis of porous scaffold biocompatibility applicable in bone tissue engineering. ALTEX, 36 (1), 121-130.
OCA18. Characteristics of the output's impact on socio-economic practice	Preclinical testing of biomaterials intended for the regeneration of hard tissues and cartilage. Using of alternative animal models in biomedicine.
OCA19. Characteristics of the output and related activities' impact on the educational process	The impact of the publication output on the educational process is mainly in the field of knowledge of the using of alternative animal models in the process of testing biomaterials.