ADC Changes in C-reactive protein, haptoglobin concentrations and some haematological parameters in female dogs before mating, during pregnancy and after parturition . Katarína Goldírová, Mária Fialkovičová, Csilla Tóthová, Jana Gálová, Edina Sesztáková, Gabriel Kováč, Terézia Pošiváková, Ján Pošivák, Marta Benková, Serena Pošiváková. In Magyar Állatorvosok Lapja. - ISSN 0025-004X. - Vol. 140, č. 2(2018), s. 85-90. (0.196

ADC Changes in C-reactive protein, haptoglobin concentrations and some haematological parameters in female dogs before mating, during pregnancy and after parturition . Katarína Goldírová, Mária Fialkovičová, Csilla Tóthová, Jana Gálová, Edina Sesztáková, Gabriel Kováč, Terézia Pošiváková, Ján Pošivák, Marta Benková, Serena Pošiváková. In Magyar Állatorvosok Lapja. - ISSN 0025-004X. - Vol. 140, č. 2(2018), s. 85-90. (0.196 - IF2018).

Basic data
OCA1. Surname awarded to the assessed person	Fialkovičová
OCA2. Name awarded to the assessed person	Mária
OCA3. Degrees awarded to the assessed person	Assoc. prof. , DVM, PhD
OCA4. Hyperlink to the entry of the person in the Register of university staff	https://www.portalvs.sk/regzam/detail/6018
OCA5. Area of assessment	study programme internal diseases of animals · III. degree
OCA6. Category of the research/artistic/other output	scientific output
OCA7. Year of publication of the research/artistic/other output	2018
OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA)	72707
OCA9. Hyperlink to the record in CRPA or CRAA	https://app.crepc.sk/?fn=detailBiblioFormChildUMCH1&sid=56829DC1A1137CAB2FFB9D2F&seo=CREP%C4%8C-detail-%C4%8Cl%C3%A1nok
Characteristics of the output that is not registered in CRPA or CRAA
OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs	https://www.webofscience.com/wos/woscc/full-record/WOS:000426144400004
OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs	ADC Changes in C-reactive protein, haptoglobin concentrations and some haematological parameters in female dogs before mating, during pregnancy and after parturition . Katarína Goldírová, Mária Fialkovičová, Csilla Tóthová, Jana Gálová, Edina Sesztáková, Gabriel Kováč, Terézia Pošiváková, Ján Pošivák, Marta Benková, Serena Pošiváková. In Magyar Állatorvosok Lapja. - ISSN 0025-004X. - Vol. 140, č. 2(2018), s. 85-90. (0.196 - IF2018).
OCA12. Type of the output (if the output is not registered in CRPA or CRAA)	article
OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.)	https://univet.hu/files/subpages/153/files/MAL-2018-02_content.pdf
OCA14. Characteristics of the author's contribution	The co-author contributed to the finalisation of the publication.
OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc.	The authors describe pre-mating, gestation and parturition of females. C-reactive protein (CRP), haptoglobin (Hp) and haematological parameters. The group consisted of 25 healthy males. These sites 6 pregnant animals from these dogs were included in the permanent group and blood samples were taken before mating. Additional blood samples were taken on days 26-30, 58-62 and on days 3, 18 and 33 after calving. The results showed statistically significant changes in CRP concentrations during gestation (α = 0.05), with a maximum increase between days 25 and 30 (27.91 ± 2.60 mg/l). Hp concentrations showed statistically significant (α = 0.05) between days 26 and 30 of gestation (4.24 ± 1.21 mg/ml) and at calving (4.24 ± 1.21 mg/ml). was recorded after calving.
Other data
OCA16. Annotation of the output in English	Acute phase proteins (APP) are generally used as non-specific markers of inflammation in dogs. The production of APP may be triggered also by physiological factors, for example pregnancy. The aim of our study was to compare serum concentrations of C-reactive protein (CRP) and haptoglobin (Hp) between pregnant and non-pregnant bitches. We determined serum concentrations of CRP, Hp, haematocrit (HCT), haemoglobin (HGB), erythrocytes (RBC), leukocytes (WBC) and mean corpuscular volume of erythrocytes (MCV) in a group of 25 healthy, non-pregnant bitches. From these animals we formed a subgroup of 6 pregnant bitches. Samples of blood were collected from them before mating during oestrus. Second sampling of blood was performed at days 26−30 of pregnancy and the third one between days 58 and 62 of pregnancy. The fourth, fifth and sixth samplings were performed on days 3, 18 and 33 post-parturition, respectively.
OCA17. List of maximum 5 most significant citations corresponding to the output
OCA18. Characteristics of the output's impact on socio-economic practice	Examinations of healthy, non-pregnant bitches showed that concentrations of CRP reached 7.23 ± 4.65 mg/l. Before mating CRP was at the level of 3.2 ± 1.90 mg/l and abruptly increased to 27.91 ± 2.60 mg/l by the second sampling. By the third sampling, CRP decreased to 13.25 ± 4.23 mg/l. On day 3 post-parturition, CRP increased to 14.44 ± 7.92 mg/l. At fifth sampling, CRP concentration decreased to 6.58 ± 2.81 mg/l. At third sampling, Hp decreased almost to the initial level before mating. Differences in concentrations of CRP and Hp at individual samplings were significant (α = 0.05). Our investigations showed significant changes in CRP during pregnancy with maximal values reached between days 25 and 30 of pregnancy.
OCA19. Characteristics of the output and related activities' impact on the educational process	The results of this research are used and explained to students in the pedagogical process and are used in the practice of small animals.