| Basic data |
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| OCA1. Surname awarded to the assessed person | Petrovová |
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| OCA2. Name awarded to the assessed person | Eva |
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| OCA3. Degrees awarded to the assessed person | Prof. , DVM, PhD |
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| OCA4. Hyperlink to the entry of the person in the Register of university staff | https://www.portalvs.sk/regzam/detail/6066 |
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| OCA5. Area of assessment | study programme veterinary morphology and physiology · III. degree |
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| OCA6. Category of the research/artistic/other output | scientific output |
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| OCA7. Year of publication of the research/artistic/other output | 2019 |
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| OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA) | ID = 135135 |
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| OCA9. Hyperlink to the record in CRPA or CRAA | https://app.crepc.sk/?fn=detailBiblioFormChildA7J2C&sid=61B9BE2C1A50DA0189E0E3FA5F&seo=CREP%C4%8C-detail-%C4%8Cl%C3%A1nok |
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| Characteristics of the output that is not registered in CRPA or CRAA |
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| OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs | https://www.webofscience.com/wos/woscc/full-record/WOS:000485306500010 |
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| OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs | ADC HUMENÍK, Filip - ČÍŽKOVÁ, Dáša - ČIKOŠ, Štefan - LUPTÁKOVÁ, Lenka - MAĎARI, Aladár - MUDROŇOVÁ, Dagmar - KURICOVÁ, Mária - FARBÁKOVÁ, Jana - ŠPIRKOVÁ, Alexandra - PETROVOVÁ, Eva - CENTE, Martin - MOJŽIŠOVÁ, Zuzana - ABOULOUARD, Soulaimane - MURGOCI, Adriana - Natalia - FOURNIER, Isabelle - SALZET, Michel. Canine bone marrow-derived mesenchymal stem cells: genomics, proteomics and functional analyses of paracrine factors. In Molecular and Cellular Proteomics. ISSN 1535-9476, 2019, vol. 18, no. 9, p. 1824-1835. (2019: 4.870 - IF, 5.865 - IF 5y, 181 - H-index, 2.355 - SJR, Q1 - SJR Best Q, Q1 - JCR Best Q). |
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| OCA12. Type of the output (if the output is not registered in CRPA or CRAA) | article |
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| OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.) | https://www.sciencedirect.com/science/article/pii/S1535947620317813?via%3Dihub |
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| OCA14. Characteristics of the author's contribution | Funding acquisition, Methodology |
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| OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc. | The aim of the study was to provide a comprehensive analysis of mesenchymal stem cells from canine bone marrow and conditioned media. Multipotent differentiation and specific surface markers were complemented by the detection of gene expression, proteomic profile and their biological function. Canine BMMSCs release a variety of bioactive molecules revealing a potent paracrine component that may have therapeutic potential in a variety of pathological conditions. |
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| Other data |
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| OCA16. Annotation of the output in English | The study aim was to provide a comprehensive analyse of canine bone marrow derived mesenchymal stem cells (BMMSC) and conditioned media, isolated from healthy adult dogs of different breeds. The multipotent differentiation and specific surface markers analyses of BMMSC were supplemented with detection of gene expression, proteomic profile, and their biological function. Canine BMMSC release a variety of bioactive molecules revealing a strong paracrine component that may possess therapeutic potential in various pathologies. |
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| OCA17. List of maximum 5 most significant citations corresponding to the output | Rahmani, A., Saleki, K., Javanmehr, N., Khodaparast, J., Saadat, P., Nouri, H.R., 2020: Mesenchymal stem cell-derived extracellular vesicle-based therapies protect against coupled degeneration of the central nervous and vascular systems in stroke. Ageing Research Reviews, 62, 101106.
Vlahovic, K., Greguric Gracner, G., Pavlak, M., Spoljaric, D., Pajurin, L., Popovic, M., 2020: Next-generation sequencing in veterinary medicine – a review: part II. Veterinarska stanica, 51 (3), 305-315.
Al Delfi, I.R.T., Wood, C.R., Johnson, L.D.V., Snow, M.D., Innes, J.F., Myint, P., Johnson, W.E.B., 2020: An in vitro comparison of the neurotrophic and angiogenic activity of human and canine adipose-derived mesenchymal stem cells (Mscs): Translating msc-based therapies for spinal cord injury. Biomolecules, 10 (9), 1-13.
Russell, K.A., Garbin, L.C., Wong, J.M., Koch, T.G., 2020: Mesenchymal stromal cells as potential antimicrobial for veterinary use – A comprehensive review. Frontiers in Microbiology, 11, 606404. |
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| OCA18. Characteristics of the output's impact on socio-economic practice | Importantly, here we determine the canine BMMSC properties applicable for replacement therapies in osteo-chondral disease as well as other tissues due to their capability of releasing immunomodulatory, angiogenic, and bioactive molecules via CM. By means of this comprehensive study, we demonstrate that canine BMMSC, similarly to human MSCs, under uniform characterization criteria represent an interesting source of stem cells that could be available for therapeutic and clinical application in veterinary practice. |
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| OCA19. Characteristics of the output and related activities' impact on the educational process | The impact of the publication output on the educational process is mainly in the field of knowledge of the using of mesenchymal stem cells in the surgery theprapies of osteochondral disease or another tissues. |
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