| Basic data |
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| OCA1. Surname awarded to the assessed person | Čížková |
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| OCA2. Name awarded to the assessed person | Daša |
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| OCA3. Degrees awarded to the assessed person | Prof. , DVM, DrSc. |
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| OCA4. Hyperlink to the entry of the person in the Register of university staff | https://www.portalvs.sk/regzam/detail/6154 |
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| OCA5. Area of assessment | study programme veterinary surgery, orthopedics and radiology · III. degree |
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| OCA6. Category of the research/artistic/other output | scientific output |
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| OCA7. Year of publication of the research/artistic/other output | 2020 |
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| OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA) | ID = 135135 |
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| OCA9. Hyperlink to the record in CRPA or CRAA | https://app.crepc.sk/?fn=detailBiblioFormChildGAQN4&sid=61B9BE2C1A50DA0189E0E3FA5F&seo=CREP%C4%8C-detail-%C4%8Cl%C3%A1nok |
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| Characteristics of the output that is not registered in CRPA or CRAA |
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| OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs | https://arl4.library.sk/arl-uvlk/sk/detail-uvlk_un_cat-0032637-Canine-bone-marrowderived-mesenchymal-stem-cells-genomics-proteomics-and-functional-analyses-of-p/?disprec=1&iset=2 |
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| OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs | ADC HUMENÍK, Filip - ČÍŽKOVÁ, Dáša - ČIKOŠ, Štefan - LUPTÁKOVÁ, Lenka - MAĎARI, Aladár - MUDROŇOVÁ, Dagmar - KURICOVÁ, Mária - FARBÁKOVÁ, Jana - ŠPIRKOVÁ, Alexandra - PETROVOVÁ, Eva - CENTE, Martin - MOJŽIŠOVÁ, Zuzana - ABOULOUARD, Soulaimane - MURGOCI, Adriana - Natalia - FOURNIER, Isabelle - SALZET, Michel. Canine bone marrow-derived mesenchymal stem cells: genomics, proteomics and functional analyses of paracrine factors. In Molecular and Cellular Proteomics. ISSN 1535-9476, 2019, vol. 18, no. 9, p. 1824-1835 |
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| OCA12. Type of the output (if the output is not registered in CRPA or CRAA) | article |
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| OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.) | https://www.sciencedirect.com/science/article/pii/S1535947620317813 |
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| OCA14. Characteristics of the author's contribution | The assessed author has a central share in the publication. Complex characteristics (based on genome and proteome) of adult stem cells isolated from the bone marrow of a dog, which could be used in tissue regeneration. |
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| OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc. | The main goal of our study was to provide a comprehensive profile of canine bone marrow-derived mesenchymal stem cells (BMMSCs) and their derived media (KM). The data obtained confirm that canine BMMSCs express important genes for differentiation towards osteo-, chondro- and tendogenic tissues, as well as genes associated with angiogenic, neurotrophic and immunomodulatory properties. Using proteome profiling, we identified for the first time in the conditioned BMMSC medium the dynamic release of bioactive molecules, such as e.g. transcription and translation factors, osteogenic, growth, angiogenic and neurotrophic factors. |
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| Other data |
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| OCA16. Annotation of the output in English | The main goal of our study was to provide a comprehensive profile of canine bone marrow-derived mesenchymal stem cells (BMMSCs) and their derived media (KM). The data obtained confirm that canine BMMSCs express important genes for differentiation towards osteo-, chondro- and tendogenic tissues, as well as genes associated with angiogenic, neurotrophic and immunomodulatory properties. Using proteome profiling, we identified for the first time in the conditioned BMMSC medium the dynamic release of bioactive molecules, such as e.g. transcription and translation factors, osteogenic, growth, angiogenic and neurotrophic factors. |
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| OCA17. List of maximum 5 most significant citations corresponding to the output | VLAHOVIĆ, K. - GREGURIĆ GRAČNER, G. - PAVLAK, M. - ŠPOLJARIĆ, D. - PAJURIN, L. - POPOVIĆ, M. Next-generation sequencing in veterinary medicine a review: part II. In Veterinarska Stanica. ISSN 03507149, 2020-01-01, 51, 3, pp. 305-315., Registrované v: Scopus
RAHMANI, Abolfazl - SALEKI, Kiarash - JAVANMEHR, Nima - KHODAPARAST, Javad - SAADAT, Payam - NOURI, Hamid Reza. Mesenchymal stem cell-derived extracellular vesicle-based therapies protect against coupled degeneration of the central nervous and vascular systems in stroke. In Ageing Research Reviews. ISSN 15681637, 2020-09-01, 62, pp., Registrované v: Scopus
AL DELFI, Ibtesam R.T. - WOOD, Chelsea R. - JOHNSON, Louis D.V. - SNOW, Martyn D. - INNES, John F. - MYINT, Peter - JOHNSON, William E.B. An in vitro comparison of the neurotrophic and angiogenic activity of human and canine adipose-derived mesenchymal stem cells (Mscs): Translating msc-based therapies for spinal cord injury. In Biomolecules, 2020-09-01, 10, 9, pp. 1-13., Registrované v: Scopus |
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| OCA18. Characteristics of the output's impact on socio-economic practice | Our results confirm that canine BMMSCs release a variety of bioactive molecules that can be used to treat various neurodegenerative diseases. |
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| OCA19. Characteristics of the output and related activities' impact on the educational process | Basic knowledge of adult stem cell differentiation is part of pedagogical education as well as possible experimental use in the clinical practice of small animals in the treatment of osteo-chondral diseases. |
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