ADC VIKARTOVSKÁ, Zuzana - KURICOVÁ, Mária - FARBÁKOVÁ, Jana - LIPTÁK, Tomáš - MUDROŇOVÁ, Dagmar - HUMENÍK, Filip - MAĎARI, Aladár - MALOVESKÁ, Marcela - SYKOVÁ, Eva - ČÍŽKOVÁ, Dáša. Stem cell conditioned medium treatment for canine spinal cord injury: pilot feasibility study. In International Journal of Molecular Sciences. ISSN 1422-0067, 2020, vol. 21, no. 14, art. no. 5129, p. [1-21].

Basic data
OCA1. Surname awarded to the assessed personČížková
OCA2. Name awarded to the assessed personDaša
OCA3. Degrees awarded to the assessed personProf. , DVM, DrSc.
OCA4. Hyperlink to the entry of the person in the Register of university staffhttps://www.portalvs.sk/regzam/detail/6154
OCA5. Area of assessmentstudy programme veterinary surgery, orthopedics and radiology · III. degree
OCA6. Category of the research/artistic/other outputscientific output
OCA7. Year of publication of the research/artistic/other output2020
OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA)ID = 198321
OCA9. Hyperlink to the record in CRPA or CRAAhttps://app.crepc.sk/?fn=detailBiblioFormChildIBC6G&sid=3846160BBFC2BE06B6D3C2F294&seo=CREP%C4%8C-detail-%C4%8Cl%C3%A1nok
Characteristics of the output that is not registered in CRPA or CRAA
OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputshttps://arl4.library.sk/arl-uvlk/sk/detail-uvlk_un_cat-0035283-Stem-cell-conditioned-medium-treatment-for-canine-spinal-cord-injury-pilot-feasibility-study/?disprec=3&iset=5
OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputsADC VIKARTOVSKÁ, Zuzana - KURICOVÁ, Mária - FARBÁKOVÁ, Jana - LIPTÁK, Tomáš - MUDROŇOVÁ, Dagmar - HUMENÍK, Filip - MAĎARI, Aladár - MALOVESKÁ, Marcela - SYKOVÁ, Eva - ČÍŽKOVÁ, Dáša. Stem cell conditioned medium treatment for canine spinal cord injury: pilot feasibility study. In International Journal of Molecular Sciences. ISSN 1422-0067, 2020, vol. 21, no. 14, art. no. 5129, p. [1-21].
OCA12. Type of the output (if the output is not registered in CRPA or CRAA) article
OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.)https://www.mdpi.com/1422-0067/21/14/5129/htm
OCA14. Characteristics of the author's contributionThe author was the central designer of the solution to the problem and significantly contributed to the final form of the publication. Design of a clinical protocol for the evaluation of systemic administration of conditioned medium obtained from MSC bone marrow from an allogeneic source (BMMSC CM) for dogs with spinal cord injury (SCI).
OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc.This is a pilot study where we used client dogs with chronic SCI, lasting more than six months. In all dogs we observed clinical-neurological improvement, evaluated using the Olba locomotor scale: after one, three and six months of BMMSC CM treatment. Goniometric measurements revealed a partial improvement in the range of motion of the joints. Bladder function improved in two affected dogs.
Other data
OCA16. Annotation of the output in EnglishThis is a pilot study where we used client dogs with chronic SCI, lasting more than six months. In all dogs we observed clinical-neurological improvement, evaluated using the Olba locomotor scale: after one, three and six months of BMMSC CM treatment. Goniometric measurements revealed a partial improvement in the range of motion of the joints. Bladder function improved in two affected dogs.
OCA17. List of maximum 5 most significant citations corresponding to the outputAL DELFI, Ibtesam R.T. - WOOD, Chelsea R. - JOHNSON, Louis D.V. - SNOW, Martyn D. - INNES, John F. - MYINT, Peter - JOHNSON, William E.B. An in vitro comparison of the neurotrophic and angiogenic activity of human and canine adipose-derived mesenchymal stem cells (Mscs): Translating msc-based therapies for spinal cord injury. In Biomolecules, 2020-09-01, 10, 9, pp. 1-13., Registrované v: Scopus
OCA18. Characteristics of the output's impact on socio-economic practiceWe conclude that multiple administration of BMMSC CM in dogs with chronic SCI is safe and could be clinically beneficial in combination with physiotherapy.
OCA19. Characteristics of the output and related activities' impact on the educational processThe results can be used for regenerative medicine and can be implemented in the pedagogical process of science education as well as medical education.

Last updated: 28.10.2026

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