| Basic data |
|---|
| OCA1. Surname awarded to the assessed person | Mojžiš |
|---|
| OCA2. Name awarded to the assessed person | Ján |
|---|
| OCA3. Degrees awarded to the assessed person | Prof. , DVM, DrSc. |
|---|
| OCA4. Hyperlink to the entry of the person in the Register of university staff | https://www.portalvs.sk/regzam/detail/14977 |
|---|
| OCA5. Area of assessment | study programme pharmacy (joint study programme) · I. + II. degree |
|---|
| OCA6. Category of the research/artistic/other output | scientific output |
|---|
| OCA7. Year of publication of the research/artistic/other output | 2015 |
|---|
| OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA) | UPJŠ.Košice.000061915 |
|---|
| OCA9. Hyperlink to the record in CRPA or CRAA | http://www.crepc.sk/portal?fn=*recview&uid=1682299&pageId=resultform&full=0 |
|---|
| Characteristics of the output that is not registered in CRPA or CRAA |
|---|
| OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs | https://pubmed.ncbi.nlm.nih.gov/26006245/ |
|---|
| OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs | ADC - Vedecké práce v zahraničných karentovaných časopisoch
IF=3.257, Q1, citované 93 x. |
|---|
| OCA12. Type of the output (if the output is not registered in CRPA or CRAA) | article |
|---|
| OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.) | https://www.mdpi.com/1422-0067/16/5/11728 |
|---|
| OCA14. Characteristics of the author's contribution | |
|---|
| OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc. | |
|---|
| Other data |
|---|
| OCA16. Annotation of the output in English | Epidemiological studies have revealed that high consumption of soy products
is associated with low incidences of hormone-dependent cancers, including breast and prostate cancer. Soybeans contain large amounts of isoflavones, such as the genistein and daidzain. It is suggested that genistein possesses pleiotropic molecular mechanisms of action including inhibition of angiogenesis. This review focuses on the antiangiogenic properties of soy isoflavonoids and examines their possible underlying mechanisms |
|---|
| OCA17. List of maximum 5 most significant citations corresponding to the output | Wang M, Wang Y, Ye F, Yu K, Wei W, Liu M, Wang R, Cui S. Exosome encapsulated ncRNAs in the development of HCC: potential circulatory biomarkers and clinical therapeutic targets. Am J Cancer Res. 2021 Aug 15;11(8):3794-3812. (IF=6,16)
Wiggs AG, Chandler JK, Aktas A, Sumner SJ, Stewart DA. The Effects of Diet and Exercise on Endogenous Estrogens and Subsequent Breast Cancer Risk in Postmenopausal Women. Front Endocrinol (Lausanne). 2021 Sep 20;12:732255. doi: 10.3389/fendo.2021.732255. (IF=5,942)
Kikuchi H, Yuan B, Hu X, Okazaki M. Chemopreventive and anticancer activity of flavonoids and its possibility for clinical use by combining with conventional chemotherapeutic agents. Am J Cancer Res. 2019 Aug 1;9(8):1517-1535. PMID: 31497340; (IF=6,16)
Wang X, Ha D, Yoshitake R, Chan YS, Sadava D, Chen S. Exploring the Biological Activity and Mechanism of Xenoestrogens and Phytoestrogens in Cancers: Emerging Methods and Concepts. Int J Mol Sci. 2021 Aug 16;22(16):8798. doi: 10.3390/ijms22168798. (IF=5,923)
Jain A, Madu CO, Lu Y. Phytochemicals in Chemoprevention: A Cost-Effective Complementary Approach. J Cancer. 2021 Apr 30;12(12):3686-3700. doi: 10.7150/jca.57776 (IF=4.207) |
|---|
| OCA18. Characteristics of the output's impact on socio-economic practice | Epidemiological studies have revealed that high consumption of soy products is associated with low incidences of hormone-dependent cancers, including breast and prostate cancer. Soybeans contain large amounts of isoflavones, such as the genistein and daidzain. Previously, it has been demonstrated that genistein, one of the predominant soy isoflavones, can inhibit several steps involved in carcinogenesis. Moreover, genistein is also a potent inhibitor of angiogenesis. This review focuses on the antiangiogenic properties of soy isoflavonoids and examines their possible underlying mechanisms. Although more studies are required to fully elucidate the mechanism of antiangiogenic action of
soy isoflavones, and more clinical trials are needed to validate their usefulness in clinical practice, experimental data have shown that genistein is a promising agent for cancer chemoprevention. |
|---|
| OCA19. Characteristics of the output and related activities' impact on the educational process | |
|---|
