ADC11 MAJCHRAK T, RATVAJ M, SABOVA L, TOPORCAK J, MOLNAR L (2025): Toxicity of oxalic acid and its toxic effect on antioxidative enzymes in honey bee larvae. Vet Med-Czech 70,
| Basic data | |
|---|---|
| OCA1. Surname awarded to the assessed person | Toporčák |
| OCA2. Name awarded to the assessed person | Juraj |
| OCA3. Degrees awarded to the assessed person | Assoc. prof. , DVM, PhD |
| OCA4. Hyperlink to the entry of the person in the Register of university staff | https://www.portalvs.sk/regzam/detail/6017 |
| OCA5. Area of assessment | study programme parasitic diseases of animals · III. degree |
| OCA6. Category of the research/artistic/other output | |
| OCA7. Year of publication of the research/artistic/other output | 2025 |
| OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA) | |
| OCA9. Hyperlink to the record in CRPA or CRAA | |
| Characteristics of the output that is not registered in CRPA or CRAA | |
| OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs | https://app.crepc.sk/?fn=ResultFormChildQG5MM&sid=0C0B449859941CA30626EE9D2C&seo=CREP%C4%8C-Zoznam-z%C3%A1znamov |
| OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs | ADC11 MAJCHRAK T, RATVAJ M, SABOVA L, TOPORCAK J, MOLNAR L (2025): Toxicity of oxalic acid and its toxic effect on antioxidative enzymes in honey bee larvae. Vet Med-Czech 70, |
| OCA12. Type of the output (if the output is not registered in CRPA or CRAA) | article |
| OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.) | https://vetmed.agriculturejournals.cz/artkey/vet-202507-0003_toxicity-of-oxalic-acid-and-its-toxic-effect-on-antioxidative-enzymes-in-honey-bee-larvae.php |
| OCA14. Characteristics of the author's contribution | |
| OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc. | The production of food of plant origin is critically dependent on the pollination ability of honey bees, whose health has been deteriorating for a long time, and whose population is declining. In our in vivo experiment on a honey bee brood at the 4-day larval stage, we tested the following concentrations of oxalic acid: 0% (control – applied distilled water), 0.87%, 1.75%, 3.5% and 7%, corresponding to doses of 0 mg, 2.61 mg, 5.25 mg, 10.5 mg, and 21 mg of oxalic acid per dm2 of honeycomb with the brood. The LC50 values (72 h) ranged between 3.17% and 3.33%. The different LC50 values obtained resulted from three different methods used to calculate this indicator. The therapeutic index (TI) of oxalic acid was set to be 1.1, indicating a high risk to the honey bee brood. We observed an increased gene expression for the detoxifying enzyme glutathione-S-transferase (GST), but did not detect an increased gene expression for superoxide dismutase (SOD1 and SOD2), which protects the organism from oxidative stress. A decrease in gene expression was observed for prophenoloxidase and hymenoptaecin, while defensin and lysozyme did not show significant changes. These results emphasise the need for the accurate dosage and application of oxalic acid in the treatment of varroosis. |
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| OCA16. Annotation of the output in English | |
| OCA17. List of maximum 5 most significant citations corresponding to the output | |
| OCA18. Characteristics of the output's impact on socio-economic practice | |
| OCA19. Characteristics of the output and related activities' impact on the educational process | |