| Basic data |
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| OCA1. Surname awarded to the assessed person | Solárová |
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| OCA2. Name awarded to the assessed person | Zuzana |
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| OCA3. Degrees awarded to the assessed person | Assoc. prof. , M.D., PhD |
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| OCA4. Hyperlink to the entry of the person in the Register of university staff | https://www.portalvs.sk/regzam/detail/15120?mode=full |
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| OCA5. Area of assessment | study programme pharmacy (joint study programme) · I. + II. degree |
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| OCA6. Category of the research/artistic/other output | scientific output |
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| OCA7. Year of publication of the research/artistic/other output | 2020 |
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| OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA) | |
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| OCA9. Hyperlink to the record in CRPA or CRAA | https://app.crepc.sk/?fn=detailBiblioFormChildUL604&sid=FC6B5E34E7354FAEF49A1B15FB&seo=CREP%C4%8C-detail-%C4%8Cl%C3%A1nok |
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| Characteristics of the output that is not registered in CRPA or CRAA |
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| OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs | https://orcid.org/0000-0002-4212-5720 |
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| OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs | Solárová Zuzana, Mazuráková Alena, Samec Marek, Kubatka Peter, Büsselberg Dietrich, Solár Peter: Anticancer potential of lichens’ secondary metabolites. Biomolecules
ADM-vedecké práce v zahraničných časopisoch registrovaných v databázach Web of Science alebo SCOPUS, IF=4,878, Q2-SJR, citované WoS 94x, Scopus 98x |
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| OCA12. Type of the output (if the output is not registered in CRPA or CRAA) | |
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| OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.) | |
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| OCA14. Characteristics of the author's contribution | |
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| OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc. | |
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| Other data |
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| OCA16. Annotation of the output in English | Lichens produce different classes of phenolic compounds, including anthraquinones, xanthones, dibenzofuranes, depsides and depsidones. Many of them have revealed effective biological activities such as antioxidant, antiviral, antibiotics, antifungal, and anticancer. Although no clinical study has been conducted yet, there are number of in vitro and in vivo studies demonstrating anticancer effects of lichen metabolites. The main goal of our work was to review most recent published papers dealing with anticancer activities of secondary metabolites of lichens and point out to their perspective clinical use in cancer management. |
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| OCA17. List of maximum 5 most significant citations corresponding to the output | WANG, Dongpeng - WANG, Xian He - YU, Xiongjie - CAO, Fengjun - CAI, Xiaojun - CHEN, Ping - LI, Minglun - FENG, Yibin - LI, Hongliang - WANG, Xuanbin. Pharmacokinetics of Anthraquinones from Medicinal Plants. In Frontiers in Pharmacology, 2021, doi: 10.3389/fphar.2021.638993. (IF=5,81)
UREÑA-VACAS, Isabel - GONZÁLEZ-BURGOS, Elena - DIVAKAR, P. K. - GÓMEZ-SERRANILLOS, M. Pilar. Lichen Depsidones with Biological Interest. In Planta Medica, 2021, doi: 10.1055/a-1482-6381. (IF 3,352)
ULUS, Gönül. Antiangiogenic properties of lichen secondary metabolites. In Phytotherapy Research, 2021. doi: 10.1002/ptr.7023. (IF=5,878)
STUDZIŃSKA-SROKA, Elżbieta - MAJCHRZAK-CELIŃSKA, Aleksandra - ZALEWSKI, Przemysław - SZWAJGIER, Dominik - BARANOWSKA-WÓJCIK, Ewa - ŻAROWSKI, Marcin - PLECH, Tomasz - CIELECKA-PIONTEK, Judyta. Permeability of hypogymnia physodes extract component—physodic acid through the blood–brain barrier as an important argument for its anticancer and neuroprotective activity within the central nervous system. In Cancers, 2021, doi: 10.3390/cancers13071717. (IF=6,639)
ŚLUSARCZYK, Joanna - ADAMSKA, Edyta - CZERWIK-MARCINKOWSKA, Joanna. Fungi and algae as sources of medicinal and other biologically active compounds: A review. In Nutrients, 2021. doi: 10.3390/nu13093178. (IF=5,429) |
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| OCA18. Characteristics of the output's impact on socio-economic practice | The work is focused towards potential anticancer effects of some natural substances. We have been dealing with this issue at the institute for a long time. This article focuses on lichen metabolites that appear to be promising new anticancer agents. |
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| OCA19. Characteristics of the output and related activities' impact on the educational process | The anticancer drugs are part of lectures for medical students. For doctoral students, the potential antitumor effect of natural substances is an important part of their study. This work can help them understand new antitumor natural substances such as lichens and their secondary metabolites. |
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