BUJŇÁK, Lukáš - HREŠKO ŠAMUDOVSKÁ, Alena - MUDROŇOVÁ, Dagmar - NAĎ, Pavel - MARCINČÁK, Slavomír - MASKAĽOVÁ, Iveta - HARČÁROVÁ, Michaela - KARAFFOVÁ, Viera - BARTKOVSKÝ, Martin. The effect of dietary humic substances on cellular immunity and blood characteristics in piglets. In: Agriculture. 2023. ISSN 2077-0472, Vol. 13, no. 3 (2023), art. no. 636, p. [1-12] (2023: 3.300 - IF, 3.500 - IF 5y, 0.607 - SJR, Q1 - SJR Best Q, Q1 - JCR Best Q)

Basic data
OCA1. Surname awarded to the assessed personMaskaľová
OCA2. Name awarded to the assessed personIveta
OCA3. Degrees awarded to the assessed personAssoc. prof. , DVM, PhD
OCA4. Hyperlink to the entry of the person in the Register of university staffhttps://www.portalvs.sk/regzam/detail/6064
OCA5. Area of assessmentstudy programme nutrition of animals and dietetics · III. degree
OCA6. Category of the research/artistic/other outputscientific output
OCA7. Year of publication of the research/artistic/other output2023
OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA)ID: 1042465
OCA9. Hyperlink to the record in CRPA or CRAAhttps://app.crepc.sk/?fn=detailBiblioForm&sid=6E72E145B6DED42F49C5E40625D6
Characteristics of the output that is not registered in CRPA or CRAA
OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs
OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputsBUJŇÁK, Lukáš - HREŠKO ŠAMUDOVSKÁ, Alena - MUDROŇOVÁ, Dagmar - NAĎ, Pavel - MARCINČÁK, Slavomír - MASKAĽOVÁ, Iveta - HARČÁROVÁ, Michaela - KARAFFOVÁ, Viera - BARTKOVSKÝ, Martin. The effect of dietary humic substances on cellular immunity and blood characteristics in piglets. In: Agriculture. 2023. ISSN 2077-0472, Vol. 13, no. 3 (2023), art. no. 636, p. [1-12] (2023: 3.300 - IF, 3.500 - IF 5y, 0.607 - SJR, Q1 - SJR Best Q, Q1 - JCR Best Q)
OCA12. Type of the output (if the output is not registered in CRPA or CRAA) article
OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.)https://www.mdpi.com/2077-0472/13/3/636
OCA14. Characteristics of the author's contributionThe author participated in the experimental part of the publication.
OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc.The aim of the study was to evaluate the influence of humic substances in feed on immunity and metabolism, with the aim of assessing the effect of supplementation of 0.5% natural humic substances on selected immunological indicators, as well as biochemical and hematological parameters in the blood of piglets. In this study, we observed a significant increase in the proportion of CD4+CD8- lymphocytes (P
Other data
OCA16. Annotation of the output in EnglishThis study’s objective was to determine the impact of dietary humic substances on immune response and blood profiles in piglets. A total of 24 crossbred piglets (Slovakian White × Landrace; 35 days old; average body weight of 11.67 kg) were allotted to two dietary groups with (experimental; 5 g·kg−1) or without (control; 0 g·kg−1) natural humic substances supplementation. In this study, we observed a significant increase of the proportion of CD4+CD8- lymphocytes (p < 0.001) in the experimental group. The results also showed a tendency for an increase of the phagocytic activity and the engulfing capacity of phagocytes and the numbers of the other monitored lymphocyte subpopulations (CD3+, CD21+, CD4-D8+, CD4+CD8+, CD4+CD25+) in piglets in the experimental group compared to the control group. Supplementation of humic substances increased serum alkaline phosphatase compared to the control group (p < 0.05). Other monitored blood parameters were not significantly affected by dietary treatment. It concluded that inclusion of humic substances in the diet of piglets could have a stimulating effect on cellular immunity, without a negative effect on haematological and biochemical parameters.
OCA17. List of maximum 5 most significant citations corresponding to the outputEdmonds, M. S., & Weber, T. E. (2023). Efficacy of water application of a humic substance, butyric acid, vitamins C, D, and E and/or electrolytes on performance and mortality in health-challenged nursery pigs¹. Translational Animal Science, 7(1), txad115. Maguey-González, J. A., Nava-Ramírez, M. D. J., Gómez-Rosales, S., Ángeles, M. D. L., Solís-Cruz, B., Hernández-Patlán, D., ... & Téllez-Isaías, G. (2023). Evaluation of the efficacy of humic acids to counteract the toxic effects of aflatoxin B1 in turkey poults. Frontiers in Veterinary Science, 10, 1276754. Roulia, M. (2024). Sustainable utilization of humic substances and organic waste in green agriculture. Agriculture, 14(1), 115.
OCA18. Characteristics of the output's impact on socio-economic practiceThe results of the study provide useful information regarding a diet supplementation with humic substances in low concentration could have a stimulatory effect on some immune cells and can positively affect cellular immunity in piglets. Due to the fact, that the concentration of humic substances we chose had a significant effect only on some indicators of cellular immunity, further studies will be necessary to choose an appropriate concentration and confirm the stimulating effect on immunity in this category of animals.
OCA19. Characteristics of the output and related activities' impact on the educational processThe publication suitably complements the study literature in pre-graduate and postgraduate education and provides a perspective on the use of feed additives - humic acids - on the quality of pig production, but also in the direction of animal health, with a confirmed direct stimulating effect on immunity.

Last updated: 28.10.2026

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