| Basic data |
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| OCA1. Surname awarded to the assessed person | Mučaji |
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| OCA2. Name awarded to the assessed person | Pavel |
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| OCA3. Degrees awarded to the assessed person | Prof. , Pharm.D., PhD |
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| OCA4. Hyperlink to the entry of the person in the Register of university staff | https://www.portalvs.sk/regzam/detail/3753 |
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| OCA5. Area of assessment | study programme pharmacy (joint study programme) · I. + II. degree |
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| OCA6. Category of the research/artistic/other output | scientific output |
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| OCA7. Year of publication of the research/artistic/other output | 2025 |
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| OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA) | ID: 1393160 |
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| OCA9. Hyperlink to the record in CRPA or CRAA | https://app.crepc.sk/?fn=detailBiblioForm&sid=95D494F54F744D915A294EFB2E70 |
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| Characteristics of the output that is not registered in CRPA or CRAA |
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| OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs | https://www.scopus.com/pages/publications/105010338059?origin=resultslist |
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| OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs | Kurin Elena, Hajská Marianna, Kostovčíková Ema, Dokupilová Kamila, Mučaji Pavel, Nagy Milan, Novotný Branislav, Bittner Fialová Silvia: Unveiling Synergistic Antioxidant Effects of Green Tea and Peppermint: Role of Polyphenol Interactions and Blend Preparation |
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| OCA12. Type of the output (if the output is not registered in CRPA or CRAA) | |
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| OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.) | https://www.mdpi.com/1422-0067/26/13/6257 |
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| OCA14. Characteristics of the author's contribution | |
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| OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc. | |
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| Other data |
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| OCA16. Annotation of the output in English | This study explores the antioxidant activity of green tea (Camellia sinensis, GT) and peppermint (Mentha × piperita, PM) infusions, individually and in combination, focusing on how preparation methods affect their efficacy. Antiradical and intracellular antioxidant activity was assessed using DPPH, ABTS, and DCF assays, alongside interaction analysis via combination index (CI) and dose reduction index (DRI). HPLC analysis determined the polyphenolic profiles of GT and PM. GT showed the strongest antioxidant activity, with the lowest IC50 values (4.81 µg/mL in DPPH, 2.70 µg/mL in ABTS, 3.71 µg/mL in DCF), indicating potent radical-scavenging potential. PM exhibited moderate antiradical capacity but similar intracellular activity (IC50 = 3.80 µg/mL). Co-maceration followed by lyophilization of GT:PM extracts led to nearly additive interactions (CI~1.0) and allowed significant dose reduction (DRI up to 4.44). In contrast, post-mixed extracts showed assay-dependent effects, including antagonism in intracellular ROS inhibition (CI = 1.83). Equimolar mixtures of model polyphenols: EGCG, quercetin, and rosmarinic acid demonstrated enhanced effects, with the strongest synergy in ternary mixtures (CI = 0.67–0.86), potentially achievable in GT:PM combinations. These findings highlight that extract preparation critically influences antioxidant efficacy, supporting co-maceration as a promising strategy for developing effective functional formulations based on plant extract combinations. |
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| OCA17. List of maximum 5 most significant citations corresponding to the output | [01 ]A. S. Bazaid, , S. A. Alsalamah, H. Qanash , M. I. Alghonaim, N. H. Saeedi, A. Aldarhami: Ozone Mediated Modulation of Green Tea Extract Enhances Bioactive Compounds and Therapeutic Potential Relevant to Human HealthPharmaceuticals 2025, 18(11), 1694; https://doi.org/10.3390/ph18111694 |
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| OCA18. Characteristics of the output's impact on socio-economic practice | |
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| OCA19. Characteristics of the output and related activities' impact on the educational process | |
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