HUDÁK, Alexander - ŠULEKOVÁ, Monika - VÁHOVSKÁ, Lucia. Optimalizácia podmienok stanovenia 5-fluóruracilu metódou UHPLC. In Folia Pharmaceutica Cassoviensia. ISSN 2585-9609, 2022, roč. 4, č. 4, s. 118-124. .

Basic data
OCA1. Surname awarded to the assessed person	Hudák
OCA2. Name awarded to the assessed person	Alexander
OCA3. Degrees awarded to the assessed person	Assoc. prof. , M.A., PhD
OCA4. Hyperlink to the entry of the person in the Register of university staff	https://www.portalvs.sk/regzam/detail/15736
OCA5. Area of assessment	study programme pharmacy (joint study programme) · I. + II. degree
OCA6. Category of the research/artistic/other output	scientific output
OCA7. Year of publication of the research/artistic/other output	2022
OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA)	ID: 187887
OCA9. Hyperlink to the record in CRPA or CRAA	https://app.crepc.sk/?fn=detailBiblioFormChildC9OHE&sid=3FA563B72988EE5765E3BF1D97&seo=CREP%C4%8C-detail-%C4%8Cl%C3%A1nok
Characteristics of the output that is not registered in CRPA or CRAA
OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs	https://www.webofscience.com/wos/woscc/full-record/WOS:000706830500042?SID=EUW1ED0E37RjtW6795rOFOlrpNGoC
OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs	HUDÁK, Alexander - ŠULEKOVÁ, Monika - VÁHOVSKÁ, Lucia. Optimalizácia podmienok stanovenia 5-fluóruracilu metódou UHPLC. In Folia Pharmaceutica Cassoviensia. ISSN 2585-9609, 2022, roč. 4, č. 4, s. 118-124. .
OCA12. Type of the output (if the output is not registered in CRPA or CRAA)	article
OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.)	https://www.uvlf.sk/document/folia-pharmaceutica-cassoviensia-volume-4-issue-4-2022.pdf
OCA14. Characteristics of the author's contribution	Performing HPLC measurements in search of optimal conditions for the determination of 5-fluorouracil and processing of materials for the paper.
OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc.
Other data
OCA16. Annotation of the output in English	This study is focused on the optimization of the method of high-performance liquid chromatography (UHPLC), with the aim to find suitable conditions for simple and fast determination of the drug 5-fluorouracil (5-FU). Based on the experimental measurements, the method of isocratic elution on a Hypersil C18 column with a reverse phase was chosen for the determination of 5-FU. The mobile phase consisted of methanol and phosphate buffer solution (pH = 6.9), in a volume ratio of 3 : 97 (v/v). The measurement was performed at a flow rate of 1.0 ml.min-1, sample injection with a volume of 20 μl and a column temperature of 25 °C. A Diode Array Detector (DAD) was used for measurement of absorbance at 268 nm. The optimized chromatographic method can be useful in biomedical applications, for the study of controlled loading and subsequent releasing of 5-FU from mesoporous silica as a drug carrier.
OCA17. List of maximum 5 most significant citations corresponding to the output
OCA18. Characteristics of the output's impact on socio-economic practice
OCA19. Characteristics of the output and related activities' impact on the educational process	The article is a contribution to expanding knowledge about the use of the HPLC method in the analysis of drug samples.