Sofie Navelsaker Thommessen, Luc Jouneau, Rosario Castro, Vanessa Mhanna, Encarnita Mariotti-Ferrandiz, Hetron M. Munang´andu, Amr Ahmed Abdelrahim Gamil, Bertrand Collet, Pierre Boudinot, Oystein Evensen: Contrasted modifications of IgM and IgT repertoires induced by high- and low-virulent infectious pancreatic necrosis virus strains in rainbow trout (Oncorhynchus mykiss). Front. Immunol., 2026, Sec. Comparative Immunology, Volume 16 - 2025 DOI: 10.3389/fimmu.2025.1690504

Basic data
OCA1. Surname awarded to the assessed personMunang’andu
OCA2. Name awarded to the assessed personHetron Mweemba
OCA3. Degrees awarded to the assessed personAssoc. prof. , DVM, PhD
OCA4. Hyperlink to the entry of the person in the Register of university staffhttps://www.nord.no/en/about/employees/hetron-mweemba-munangandu
OCA5. Area of assessmentstudy programme animal science · I. degree
OCA6. Category of the research/artistic/other outputscientific output
OCA7. Year of publication of the research/artistic/other output2026
OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA)
OCA9. Hyperlink to the record in CRPA or CRAA
Characteristics of the output that is not registered in CRPA or CRAA
OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputshttps://pubmed.ncbi.nlm.nih.gov/41717442/
OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputsSofie Navelsaker Thommessen, Luc Jouneau, Rosario Castro, Vanessa Mhanna, Encarnita Mariotti-Ferrandiz, Hetron M. Munang´andu, Amr Ahmed Abdelrahim Gamil, Bertrand Collet, Pierre Boudinot, Oystein Evensen: Contrasted modifications of IgM and IgT repertoires induced by high- and low-virulent infectious pancreatic necrosis virus strains in rainbow trout (Oncorhynchus mykiss). Front. Immunol., 2026, Sec. Comparative Immunology, Volume 16 - 2025 DOI: 10.3389/fimmu.2025.1690504
OCA12. Type of the output (if the output is not registered in CRPA or CRAA) article
OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.)https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1690504/full
OCA14. Characteristics of the author's contributionCo-author
OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc.This study describes how different clones of fish immunoglobulin M (igM) respond to infectious pancreatic necrosis virus infection. It also described the activation og the immunoglobulin T (igT) which is found on the surface as a mucosal antibody in fish. It shows a clear contrast between the mucosal antibody (IgT) and the blood circulatory antibody (igM) in fish in response to activation by the virus (IPNV).. This study can be used to understand the functional mechanisms of different immunoglobulins found in fish in response to viral infections.
Other data
OCA16. Annotation of the output in EnglishThis study describe how different IgM clonal types response to infection by the virus (infectious pancreatic necrosis virus) in rainbow trout.
OCA17. List of maximum 5 most significant citations corresponding to the outputdoi: 10.1016/j.fsi.2026.111371 doi: 10.3389/fimmu.2026.1759765 doi: 10.1016/j.dci.2026.105593 doi: 10.1016/j.fsi.2025.110397 doi: 10.3389/fimmu.2024.1490776
OCA18. Characteristics of the output's impact on socio-economic practiceThis study show how the mucosal and systemic fish immunoglobulin respond to viral infections and the mechanisms used to develop long term immune response to infection based on fish immunoglobulins
OCA19. Characteristics of the output and related activities' impact on the educational processThe study can be used to explain the different functions of fish immunoglobulin to students. Also, it can be used to show students aspects of comparative immunology the show that fish use IgT as a mucosal immunoglobulin unlike humans/animals that use IgA. it also shows that fish use IgM as the main systemic antibody unlike animals/humans that use both IgM and IgG as the main protective antibodies.

Last updated: 28.10.2026

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