Antiadhesive effects of exopolysaccharides isolated from Limosilactobacillus reuteri

Basic data
OCA1. Surname awarded to the assessed person	Prokeš
OCA2. Name awarded to the assessed person	Marián
OCA3. Degrees awarded to the assessed person	Assoc. prof. , DVM, PhD
OCA4. Hyperlink to the entry of the person in the Register of university staff	https://www.portalvs.sk/regzam/detail/6118
OCA5. Area of assessment	study programme man-animal relationship and its use in canistherapy and hipotherapy · I. degree
OCA6. Category of the research/artistic/other output
OCA7. Year of publication of the research/artistic/other output	2025
OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA)	1423405
OCA9. Hyperlink to the record in CRPA or CRAA	https://app.crepc.sk/?fn=detailBiblioForm&sid=83712EB9BC21748F2E9B5B10A71B
Characteristics of the output that is not registered in CRPA or CRAA
OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs	https://www.scopus.com/pages/publications/105013035388?origin=resultslist
OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs	Antiadhesive effects of exopolysaccharides isolated from Limosilactobacillus reuteri
OCA12. Type of the output (if the output is not registered in CRPA or CRAA)	article
OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.)	https://office2.jmbfs.org/index.php/JMBFS/article/view/11574
OCA14. Characteristics of the author's contribution	Editing the article.
OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc.	Probiotics with their biological properties and products contribute to optimal functioning of organ systems and form a natural barrier against the growth of undesirable microorganisms. Exopolysaccharides (EPS) isolated from selected strains of Lactobacilli are tested for their antiadhesive, anti-biofilm and other beneficial effects. EPS isolated from the SL16 strain of Limosilactobacillus reuteri (formerly Lactobacillus reuteri) significantly reduced adhesion of Staphylococcus aureus CCM 3953 and Proteus mirabilis CCM 7188, and this effect was directly proportional to EPS concentration and stronger against S. aureus CCM 3953. Achieved results indicated an anti-biofilm potential of EPS obtained from intestinal Lactobacilli, probably attributable to antiadhesive activity of the tested EPS. Further studies will be required in order to clarify a mechanism of the anti-biofilm effect at the molecular level. Within the research into innovative anti-biofilm agents (biodegradable and non-toxic), the results obtained may facilitate the development of more efficient procedures or preparations that will be used in pharmacotherapy.
Other data
OCA16. Annotation of the output in English	Probiotics with their biological properties and products contribute to optimal functioning of organ systems and form a natural barrier against the growth of undesirable microorganisms. Exopolysaccharides (EPS) isolated from selected strains of Lactobacilli are tested for their antiadhesive, anti-biofilm and other beneficial effects. EPS isolated from the SL16 strain of Limosilactobacillus reuteri (formerly Lactobacillus reuteri) significantly reduced adhesion of Staphylococcus aureus CCM 3953 and Proteus mirabilis CCM 7188, and this effect was directly proportional to EPS concentration and stronger against S. aureus CCM 3953. Achieved results indicated an anti-biofilm potential of EPS obtained from intestinal Lactobacilli, probably attributable to antiadhesive activity of the tested EPS. Further studies will be required in order to clarify a mechanism of the anti-biofilm effect at the molecular level. Within the research into innovative anti-biofilm agents (biodegradable and non-toxic), the results obtained may facilitate the development of more efficient procedures or preparations that will be used in pharmacotherapy.
OCA17. List of maximum 5 most significant citations corresponding to the output	Ismail, N. I., Nawawi, K. N. M., Hsin, D. C. C., Hao, K. W., Mahmood, N. R. K. N., Chearn, G. L. C., Wong, Z., Tamil, A. M., Joseph, H., & Raja Ali, R. A. (2023). Probiotic containing Lactobacillus reuteri DSM 17648 as an adjunct treatment for Helicobacter pylori infection: A randomized, double-blind, placebo-controlled trial. Helicobacter, 28(6), e13017. https://doi.org/10.1111/hel.13017
OCA18. Characteristics of the output's impact on socio-economic practice	Within the research into innovative anti-biofilm agents (biodegradable and non-toxic), the results obtained may facilitate the development of more efficient procedures or preparations that will be used in pharmacotherapy.
OCA19. Characteristics of the output and related activities' impact on the educational process	The impacts and results of the work will be reflected in the teaching of study subjects with an epizootiological content.