| Basic data |
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| OCA1. Surname awarded to the assessed person | Petrilla |
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| OCA2. Name awarded to the assessed person | Vladimír |
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| OCA3. Degrees awarded to the assessed person | Assoc. prof. , DVM, PhD |
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| OCA4. Hyperlink to the entry of the person in the Register of university staff | https://www.portalvs.sk/regzam/detail/23878 |
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| OCA5. Area of assessment | study programme man-animal relationship and its use in canistherapy and hipotherapy · I. degree |
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| OCA6. Category of the research/artistic/other output | scientific output |
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| OCA7. Year of publication of the research/artistic/other output | 2024 |
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| OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA) | ID = 1165022 |
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| OCA9. Hyperlink to the record in CRPA or CRAA | https://app.crepc.sk/?fn=detailBiblioForm&sid=F2CC723B7B1D671C2D2AABF2AE77 |
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| Characteristics of the output that is not registered in CRPA or CRAA |
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| OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs | https://arl4.library.sk/arl-uvlk/sk/detail-uvlk_un_cat-0043682-Venom-diversity-in-Naja-mossambica-Insights-from-proteomic-and-immunochemical-analyses-reveal-intra/?disprec=1&iset=9 |
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| OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs | HUS, Konrad Kamil - BUCZKOWICZ, Justyna - PIETROWSKA, Monika - PETRILLA, Vladimír - PETRILLOVÁ, Monika - LEGÁTH, Jaroslav - LITSCHKA-KOEN, Thea - BOCIAN, Aleksandra. Venom diversity in Naja mossambica: Insights from proteomic and immunochemical analyses reveal intraspecific differences. In PLOS Neglected Tropical Diseases. ISSN 1935-2727, 2024, vol. 18, no. 4, art. no. 0012057, p. [1-27]. (2024: 3.4 - IF, 3.8 - IF 5y, 172 - H-index, 1.37 - SJR, Q1 - SJR Best Q, Q1 - JCR Best Q). Dostupné na internete: . |
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| OCA12. Type of the output (if the output is not registered in CRPA or CRAA) | article |
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| OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.) | https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0012057 |
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| OCA14. Characteristics of the author's contribution | Experimental preparation involving the collection of snake venoms, the performance of partial immunological analyses, as well as partial professional preparation of a scientific manuscript. |
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| OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc. | Intraspecific variations in snake venom composition have been extensively documented, contributing to the diverse clinical effects observed in envenomed patients. Understanding these variations is essential for developing effective snakebite management strategies and targeted antivenom therapies. We aimed to comprehensively investigate venoms from three distinct populations of N. mossambica from Eswatini, Limpopo, and KwaZulu-Natal regions in Africa in terms of their protein composition and reactivity with three commercial antivenoms (SAIMR polyvalent, EchiTAb+ICP, and Antivipmyn Africa). |
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| Other data |
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| OCA16. Annotation of the output in English | Intraspecific variations in snake venom composition have been extensively documented, contributing to the diverse clinical effects observed in envenomed patients. Understanding these variations is essential for developing effective snakebite management strategies and targeted antivenom therapies. We aimed to comprehensively investigate venoms from three distinct populations of N. mossambica from Eswatini, Limpopo, and KwaZulu-Natal regions in Africa in terms of their protein composition and reactivity with three commercial antivenoms (SAIMR polyvalent, EchiTAb+ICP, and Antivipmyn Africa). |
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| OCA17. List of maximum 5 most significant citations corresponding to the output | LAFNOUNE, Ayoub - CHBEL, Asmaa - DARKAOUI, Bouchra - NAIT IRAHAL, Imane - OUKKACHE, Naoual. Cobra Venom: From Envenomation Syndromes to Therapeutic Innovations. In International Journal of Peptide Research and Therapeutics, 2024-11-01, 30, 6, pp. ISSN 15733149. Dostupné na: https://doi.org/10.1007/s10989-024-10646-2., WOS, SCOPUS
BANDE, Moumouni - DELPORTE, Cédric - SAKIRA, Abdoul Karim - BOUREZ, Axelle - IMBAULT, Virginie - BISTEAU, Xavier - SOMBIE, Charles - SOME, Touridomon Issa - ANTWERPEN, Pierre Van. Development of an analytical model for assessing the adsorptive properties of traditional medicinal formulations from Burkina Faso in relation to snake venom proteins. In Toxicon, 2025-10-01, 265, pp. ISSN 00410101. Dostupné na: https://doi.org/10.1016/j.toxicon.2025.108470., WOS, SCOPUS
LE ROUX, Anandie - CLOETE, Stephanus J. - PETZER, Jacobus P. - PETZER, Anel. In vitro inhibition of snake venom toxins by varespladib, marimastat, nafamostat and dimercaprol. In TOXICON, 2025, vol. 268, no., pp. ISSN 0041-0101. Dostupné na: https://doi.org/10.1016/j.toxicon.2025.108626., WOS
CHEN, Meng Meng - TIAN, Han Wen - CHENG, Yuan Qiu - YUE, Yu Xin - PAN, Yu Chen - GUO, Dong Sheng. Broad-Spectrum Detoxification of Snake Venoms With Supramolecular Materials Integrated via Molecular Recognition and Coassembly. Dostupné na: https://doi.org/10.1002/adhm.202402732. ISSN 21922640., SCOPUS |
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| OCA18. Characteristics of the output's impact on socio-economic practice | The output has a significant impact on socio-economic practice, particularly in the fields of public health, clinical medicine, and pharmaceutical development of antivenoms. In healthcare practice, it contributes to a more accurate understanding of venom composition variability among different populations of Naja mossambica, which is crucial for the correct diagnosis and treatment of patients following envenomation. The findings may help physicians better estimate the effectiveness of available antivenoms and optimize therapeutic approaches depending on the geographic origin of the venom.In public health, the research supports more efficient planning of antivenom supply and their regional targeting, which can reduce mortality and complications associated with snakebites, particularly in African countries with a high incidence of envenomation. From a pharmaceutical perspective, the results provide important information for the development and testing of both polyvalent and specific antivenoms, as well as for evaluating their efficacy against different populations of the same species. This may lead to improved quality in antivenom production and more efficient use of resources. Economically, the output contributes to reducing costs associated with ineffective treatments and hospitalizations, thereby increasing the efficiency of healthcare systems. |
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| OCA19. Characteristics of the output and related activities' impact on the educational process | The output and related research activities have a significant educational impact, particularly in the fields of biomedicine, toxicology, veterinary medicine, and pharmaceutical sciences. First, they expand students’ theoretical knowledge of intraspecific variability in snake venoms and its clinical implications. The specific case of different populations of Naja mossambica enables a better understanding of how geographic variation influences venom composition, its biological activity, and antivenom efficacy. At the same time, the output supports the development of practical skills in interpreting proteomic data, comparing the reactivity of biological samples with commercial antivenoms, and evaluating their effectiveness. Students thus learn to connect laboratory findings with clinical and therapeutic contexts. An important educational benefit is also the strengthening of critical thinking and the ability to analyze complex biological systems, where small variations in venom composition can lead to significant differences in treatment outcomes. The related activities further promote interdisciplinary education by linking toxicology, immunology, proteomics, and public health. This contributes to the modernization of teaching and better prepares students to address real clinical and research challenges in the field of envenomation. |
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