HUMENÍK, Filip - MALOVESKÁ, Marcela - HUDÁKOVÁ, Nikola - PETROUŠKOVÁ, Patrícia - ŠUFLIARSKA, Zuzana - HORŇÁKOVÁ, Ľubica - VALENČÁKOVÁ, Alexandra - KOŽÁR, Martin - ŠIŠKOVÁ, Barbora - MUDROŇOVÁ, Dagmar - BARTKOVSKÝ, Martin - ČÍŽKOVÁ, Dáša. Impact of canine amniotic mesenchymal stem cell conditioned media on the wound healing process: In vitro and in vivo study. In: International Journal of Molecular Sciences. 2023. ISSN 1422-0067, Vol. 24, no. 9 (2023), art. no. 8214, p. [1-14] (2023: 4.900 - IF, 5.600 - IF 5y, 1.179 - SJR, Q1 - SJR Best Q, Q1 - JCR Best Q) (2023: 4.700 - IF, 4.900 - IF 5y, 0.800 - SJR, Q1 - SJR Best Q, Q1 - JCR Best Q)

Basic data
OCA1. Surname awarded to the assessed personKožár
OCA2. Name awarded to the assessed personMartin
OCA3. Degrees awarded to the assessed personAssoc. prof. , DVM, PhD
OCA4. Hyperlink to the entry of the person in the Register of university staffhttps://www.portalvs.sk/regzam/detail/20441
OCA5. Area of assessmentstudy programme veterinary nurse · I. degree
OCA6. Category of the research/artistic/other outputscientific output
OCA7. Year of publication of the research/artistic/other output2023
OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA)ID: 1054110
OCA9. Hyperlink to the record in CRPA or CRAAhttps://app.crepc.sk/?fn=detailBiblioForm&sid=C9F2ED9DAFACD725E46459E63EB7
Characteristics of the output that is not registered in CRPA or CRAA
OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputshttps://vsk.uvlf.sk/sk/view_pub/?id=0042089
OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputsHUMENÍK, Filip - MALOVESKÁ, Marcela - HUDÁKOVÁ, Nikola - PETROUŠKOVÁ, Patrícia - ŠUFLIARSKA, Zuzana - HORŇÁKOVÁ, Ľubica - VALENČÁKOVÁ, Alexandra - KOŽÁR, Martin - ŠIŠKOVÁ, Barbora - MUDROŇOVÁ, Dagmar - BARTKOVSKÝ, Martin - ČÍŽKOVÁ, Dáša. Impact of canine amniotic mesenchymal stem cell conditioned media on the wound healing process: In vitro and in vivo study. In: International Journal of Molecular Sciences. 2023. ISSN 1422-0067, Vol. 24, no. 9 (2023), art. no. 8214, p. [1-14] (2023: 4.900 - IF, 5.600 - IF 5y, 1.179 - SJR, Q1 - SJR Best Q, Q1 - JCR Best Q) (2023: 4.700 - IF, 4.900 - IF 5y, 0.800 - SJR, Q1 - SJR Best Q, Q1 - JCR Best Q)
OCA12. Type of the output (if the output is not registered in CRPA or CRAA) article
OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.)https://www.mdpi.com/1422-0067/24/9/8214
OCA14. Characteristics of the author's contributionThe author describes the use of a combination of mesenchymal stem cells and conditioned medium in the treatment of skin defects as one of the alternative therapeutic options in the conservative management of skin defects. The original contribution lies in the proposed therapy and the selection of mesenchymal stem cells as a suitable unconventional therapeutic method following the failure of standard therapeutic procedures.
OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc.
Other data
OCA16. Annotation of the output in EnglishThe study examines how conditioned medium and canine mesenchymal stem cells can aid in wound healing. Under laboratory conditions, it was shown to promote cell growth and migration, which is important for tissue regeneration. In the practical part of the study, dogs with complicated, long-healing wounds were treated with this medium in combination with standard therapy. The results showed significantly faster wound reduction and better healing quality compared to conventional treatment. The findings suggest that this is a promising and less invasive method that could improve wound treatment in veterinary medicine.
OCA17. List of maximum 5 most significant citations corresponding to the output[1] PICAZO, Rosa Ana - ROJO, Concepción - RODRIGUEZ-QUIROS, Jesus - GONZÁLEZ-GIL, Alfredo. Current Advances in Mesenchymal Stem Cell Therapies Applied to Wounds and Skin, Eye, and Neuromuscular Diseases in Companion Animals. In Animals, 2024-05-01, 14, 9, pp. Dostupné na: https://doi.org/10.3390/ani14091363., Registrované v: WOS, SCOPUS [3] MAKSIMOVA, M.A. - KOROCHKINA, E.A. Derivatives of mesenchymal stromal cells: methods of preparation and scope of application in veterinary medicine (review). In Legal regulation in veterinary medicine. ISSN 2782-6252, 2024, vol. ,no. 2, p. 75-80. [1] CHAE, Chang Woo - KIM, Dae Hyun - JO, Hyo Youn - OH, Yeon Ju - LEE, Hyun Jik. Exosomes-based applications in companion animals: Diagnostics and therapeutics in dogs and cats. In Journal of Drug Delivery Science and Technology, 2025-06-01, 108, pp. ISSN 17732247. Dostupné na: https://doi.org/10.1016/j.jddst.2025.106958., Registrované v: WOS, SCOPUS [1] GUGJOO, Mudasir Bashir. Stem Cell-Based Regenerative Medicine in Canine Practice. In Stem Cell Based Regenerative Medicine in Canine Practice, 2025-01-01, pp. 1-553. ISBN [9781394253258, 9781394253289]. Dostupné na: https://doi.org/10.1002/9781394253289., Registrované v: SCOPUS [1] YI, Ruiqi - YANG, Xiaolu - TIAN, Ya - ZHANG, Fen - ANAYYAT, Umer - ZHANG, Xiaoting - WANG, Xiaomei. Exosomes from Different Sources in Promoting Wound Healing. In Recent Advances in Drug Delivery and Formulation, 2025-01-01, 19, 3, pp. 221-234. ISSN 26673878. Dostupné na: https://doi.org/10.2174/0126673878366772250116082511., Registrované v: SCOPUS
OCA18. Characteristics of the output's impact on socio-economic practiceThis publication summarizes valuable information and findings from an evaluation of the treatment of extensive skin defects using conservative wound management. Secondary healing of open skin defects presents challenges in reducing the frequent occurrence of complications, promoting tissue repair, forming new missing structures, and ensuring functional repair of damaged tissues. A major advantage is the development and potential application of an alternative treatment option for open skin defects in small animal clinical practice.
OCA19. Characteristics of the output and related activities' impact on the educational processThis publication summarizes valuable information and findings from the evaluation of treatment for extensive skin defects using conservative wound care. Secondary healing of open skin defects presents challenges in reducing the high incidence of complications, promoting tissue regeneration, forming new missing structures, and ensuring functional restoration of damaged tissues. The main benefit is the development and potential application of an alternative treatment option for open skin defects in clinical practice in small animals.

Last updated: 28.10.2026

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