Efficacy of intravaginal lactic acid bacteria, cell-free supernatant, or Enrofloxacin on vaginitis and fertility in ewes synchronized with progesterone-based protocol / Guner, Baris; Erkan, Aslihan Ayalp; Ozturk, Buse; Guner, Tevhide Elif; Kisadere, Ihsan; Demirbilek, Serpil Kahya; Keskin, Abdulkadir; Zigo, František. – [recenzované]. – DOI 10.3390/agriculture14040604. – CCC ; WOS CC ; SCO. In: Agriculture [elektronický dokument] . – Bazilej (Švajčiarsko) : Multidisciplinary Digital Publishing Institute. – ISSN (online) 2077-0472. – Roč. 14, č. 4 (2024), art. no. 604, s. [1-10] [online]

Basic data
OCA1. Surname awarded to the assessed person	Zigo
OCA2. Name awarded to the assessed person	František
OCA3. Degrees awarded to the assessed person	Assoc. prof. , DVM, PhD
OCA4. Hyperlink to the entry of the person in the Register of university staff	https://www.portalvs.sk/regzam/detail/20442
OCA5. Area of assessment	habilitation and inauguration procedure – general veterinary medicine
OCA6. Category of the research/artistic/other output	scientific output
OCA7. Year of publication of the research/artistic/other output	2024
OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA)	ID: 1168806
OCA9. Hyperlink to the record in CRPA or CRAA	https://app.crepc.sk/?fn=ResultFormChildQ184SP&seo=CREP%C4%8C-Zoznam-z%C3%A1znamov
Characteristics of the output that is not registered in CRPA or CRAA
OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs
OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs	Efficacy of intravaginal lactic acid bacteria, cell-free supernatant, or Enrofloxacin on vaginitis and fertility in ewes synchronized with progesterone-based protocol / Guner, Baris; Erkan, Aslihan Ayalp; Ozturk, Buse; Guner, Tevhide Elif; Kisadere, Ihsan; Demirbilek, Serpil Kahya; Keskin, Abdulkadir; Zigo, František. – [recenzované]. – DOI 10.3390/agriculture14040604. – CCC ; WOS CC ; SCO. In: Agriculture [elektronický dokument] . – Bazilej (Švajčiarsko) : Multidisciplinary Digital Publishing Institute. – ISSN (online) 2077-0472. – Roč. 14, č. 4 (2024), art. no. 604, s. [1-10] [online]
OCA12. Type of the output (if the output is not registered in CRPA or CRAA)
OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.)	https://doi.org/10.3390/agriculture14040604
OCA14. Characteristics of the author's contribution	The author is the co- owner of the conceptual plan of the publication; he participated in the interpretation of the results, the final form of the publication, and financial participation.
OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc.
Other data
OCA16. Annotation of the output in English	An intravaginal sponge impregnated with progesterone is commonly used for estrus induction and synchronization in ewes. Although using an intravaginal sponge containing progesterone positively affects the synchronization rate, varying degrees of vaginitis occur during its application. This study aimed to investigate the impacts of various intravaginal treatment options on the vaginitis severity and pregnancy rate in Merino ewes synchronized with intravaginal sponges impregnated with progesterone. Varying degrees of vaginal discharge were observed in all the groups at sponge removal. The injection of enrofloxacin into the sponges reduced the vaginal discharge scores and sponge odor scores. Lactobacillus plantarum or its cell-free supernatant did not cause any adverse effects in ewes when used as an alternative strategy to antibiotic treatment. The groups receiving Lactobacillus plantarum and Lactobacillus plantarum supernatants exhibited similar pregnancy rates to the control group. However, the group treated with enrofloxacin tended to have higher pregnancy rates.
OCA17. List of maximum 5 most significant citations corresponding to the output	Toquet M., Gomis J., Jiménez-Trigos E., Bataller E., Barba M., Sánchez A., González-Torres P., Gómez-Martín Á. Development of an innovative intravaginal model of probiotic inoculation in dairy ovine flocks: positive effects on the vaginal microbiota, vaginitis and fertility. (2025) Animal, 19 (2), art. no. 101417, DOI: 10.1016/j.animal.2024.101417 Silva J.A., Vasquetto A., Mouguelar H., Nader-Macías M.E.F., Pellegrino M.S. Characterization of surface properties and antimicrobial activity of autochthonous lactic acid bacteria isolated from the reproductive tract of healthy mares. (2026) Theriogenology, 1, 252, art. no.117760 DOI: 10.1016/j.theriogenology.2025.117760 Ghafil M.J., Taie, M.A.K., Mohammed, A.K. Comparative Effects of Intravaginal Progesterone Sponge Durations (Short vs. Long Duration) With or Without Probiotics on Vaginal Microbiota Balance and Reproductive Performance in Black Iraqi Goats. (2026) Veterinary Medicine International, 1, art. no. 2031122, DOI: 10.1155/vmi/2031122 Alkass J.E., Mustafa, S.A. Comparative effects of intravaginal progesterone sponge durations and Lactobacillus spp. on vaginal microbiota, discharge, and fertility in Black Iraqi goats. (2026) Veterinary Medicine International, 2026, 10, art. no. 2031122, DOI: 10.1155/vmi/2031122. Quereda J.J., Barba M., Mocé M.L., García-Muñoz, A. Development of an innovative intravaginal model of probiotic inoculation: Positive effects on the vaginal microbiota, vaginitis and fertility in sheep. (2025) Animal, 19(2), art. no. 101417, DOI: https://doi.org/10.1016/j.animal.2024.101417
OCA18. Characteristics of the output's impact on socio-economic practice	The impact of the study closely relates to the use and comparison of the effectiveness of antibiotics and probiotics in ruminant farming practices, which will raise awareness of antimicrobial resistance and the possibilities of alternative treatments.
OCA19. Characteristics of the output and related activities' impact on the educational process	The study provides an excellent practical example of integrating knowledge from veterinary medicine, gynecology, microbiology, pharmacology, and animal reproductive biotechnology. Students can gain an understanding of the practical importance of clinical monitoring of animals during estrus synchronization and its impact on fertility.