| Basic data |
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| OCA1. Surname awarded to the assessed person | Nagy |
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| OCA2. Name awarded to the assessed person | Jozef |
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| OCA3. Degrees awarded to the assessed person | Prof. , DVM, PhD |
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| OCA4. Hyperlink to the entry of the person in the Register of university staff | https://www.portalvs.sk/regzam/detail/6021 |
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| OCA5. Area of assessment | habilitation and inauguration procedure – food hygiene and the environment |
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| OCA6. Category of the research/artistic/other output | scientific output |
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| OCA7. Year of publication of the research/artistic/other output | 2021 |
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| OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA) | ID: 414994 |
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| OCA9. Hyperlink to the record in CRPA or CRAA | https://app.crepc.sk/?fn=detailBiblioForm&sid=BD8873FEBC965481A59310BA7E |
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| Characteristics of the output that is not registered in CRPA or CRAA |
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| OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs | https://vsk.uvlf.sk/sk/view_pub/?id=0037998 |
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| OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs | \"ADC/V3 MUDROŇOVÁ, Dagmar - KARAFFOVÁ, Viera - SEMJON, Boris - NAĎ, Pavel - KOŠČOVÁ, Jana - BARTKOVSKÝ, Martin - MAKIŠ, Andrej - BUJŇÁK, Lukáš - NAGY, Jozef - MOJŽIŠOVÁ, Jana - MARCINČÁK, Slavomír. Effects of dietary supplementation of humic substances on production parameters, immune status and gut microbiota of laying hens. In: Agriculture. 2021. ISSN 2077-0472, Vol. 11, no. 8 (2021), art. no. 744,p. [1-14]
(2021: 3.408 - IF, 43 - H-index, 3.459 - IF 5y, 0.525 - SJR, Q2 - SJR Best Q, Q1 - JCR Best Q)\" |
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| OCA12. Type of the output (if the output is not registered in CRPA or CRAA) | |
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| OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.) | článok/ article |
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| OCA14. Characteristics of the author's contribution | Organization of the experiment and calculation of the addition of humic substances to the feed of broiler chickens; participation in physicochemical analyses of meat samples |
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| OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc. | This study examined the effect of a 0.5% addition of humic substances on specific production parameters related to the mineral quality of eggshells, immune parameters (relative expression of IgA, IGF-2, and the MUC-2 gene in the cecum; phagocyte activity, and the percentage of selected lymphocyte subpopulations in peripheral blood) as well as the number of lactic acid bacteria and enterobacteria in the intestinal contents of laying hens. The addition of 0.5% humic substances to laying hen feed had a positive effect on egg production, daily egg weight, egg weight, feed conversion, and eggshell quality, and also had an immunostimulatory effect manifested by increased phagocyte activity and B-cell response. At the same time, an increase in the number of enterobacteria in the intestinal contents and a decrease in the proportion of T lymphocytes (p < 0.05) were observed, which can be considered a negative effect of humic substances. The results confirmed that HS can be used to improve egg production and provide targeted immunostimulation, but its effects on the intestinal microbiota and T lymphocytes should be investigated in greater detail. |
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| Other data |
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| OCA16. Annotation of the output in English | In this study, the influence of 0.5% HS supplementation on the specific production parameters of eggshell mineral quality, immune parameters (relative expression of IgA, IGF-2, MUC-2 gene in cecum; activity of phagocytes, percentage of selected lymphocyte subpopulations in the peripheral blood), and number of lactic acid bacteria and enterobacteria in the intestinal contents in laying hens was tested. The addition of 0.5% HS to the laying hen feed had a positive effect on egg laying rate, daily egg mass, egg weight, feed conversion and eggshell quality and also had an immunostimulatory effect manifested by increased phagocyte activity and B cell response. Concurrently, an increase in the number of enterobacteria in the intestinal contents and a decrease in the proportion of T lymphocytes (p < 0.05) was observed, which can be considered as a negative effect of HS. The results confirmed that HS can be used for the improvement of egg production and targeted immunostimulation, but their effect on the intestinal microbiota and T lymphocytes should be studied in more detail. |
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| OCA17. List of maximum 5 most significant citations corresponding to the output | 2023: [1] HUANG, Jiazhang - XU, Pengfei - SHAO, Mingzhi - WEI, Bin - ZHANG, Cong - ZHANG, Jie. Humic acids alleviate dextran sulfate sodium-induced colitis by positively modulating gut microbiota. In Frontiers in Microbiology, 2023-01-01, 14, pp. Dostupné na: https://doi.org/10.3389/fmicb.2023.1147110;
[1] SUN, M.Y. - SHI, Y.L. - LEI, B.S. - ZHANG, W.C. - FENG, J.J. - GE, S.H. - YUAN, W.Z. - ZHAO, K. A pH-triggered self-releasing humic acid hydrogel loaded with porcine interferon α/γ achieves anti-pseudorabies virus effects by oral administration. In Veterinary record. ISSN 0928-4249, vol. 55, no. 1, art. no. 153;
2025: [1] SANTOS, Thays Cristina dos - SILVA, Hellen Paulo - LIMA, Karen Rodrigues - SALVADOR, Maria Luiza Nonato - CÂNDIDO, Geraldo de Sousa - PIMENTA, Laura Cristina Jardim Pôrto - BERTOLINI, Natália Oliveira - RIBEIRO, Luciana Botelho - FAGUNDES, Filipe Gomes - ORLANDO, Débora Ribeiro - BORGES, Bruno Del Bianco - DIAS-PEIXOTO, Marco Fabrício - MACHADO, Alan Rodrigues Teixeira - DOBBSS, Leonardo Barros - PEREIRA, Luciano José - ANDRADE, Eric Francelino. Humic Acid Derived from Vermicompost Improves Bone Mineral Content and Alters Oxidative Stress Markers in Ovariectomized Mice. In Biomedicines, 2025-02-01, 13, 2, pp. Dostupné na: https://doi.org/10.3390/biomedicines13020495;
[1] ORLANDO, Patrícia Ribeiro - TAVARES, Hugo Giordano - DE SOUZA PEREIRA, Ramona Ramalho - SILVA, Gabriela - CARVALHO, Jaqueline do Carmo Lima - MACHADO, Alan Rodrigues Teixeira - DOBBSS, Leonardo Barros - DIAS PEIXOTO, Marco Fabrício - PEREIRA, Luciano José - ANDRADE, Eric Francelino. Humic Acid Derived from Agricultural Biomass Mitigates Alveolar Bone Loss and Modulates Systemic Inflammatory Cytokines in Rats with Periodontitis. In Current Topics in Medicinal Chemistry, 2025-01-01, 25, 5, pp. 645-656. ISSN 15680266. Dostupné na: https://doi.org/10.2174/0115680266302476240510115556;
2025: [1] ORLANDO, Patrícia Ribeiro - TAVARES, Hugo Giordano - DE SOUZA PEREIRA, Ramona Ramalho - SILVA, Gabriela - CARVALHO, Jaqueline do Carmo Lima - MACHADO, Alan Rodrigues Teixeira - DOBBSS, Leonardo Barros - DIAS PEIXOTO, Marco Fabrício - PEREIRA, Luciano José - ANDRADE, Eric Francelino. Humic Acid Derived from Agricultural Biomass Mitigates Alveolar Bone Loss and Modulates Systemic Inflammatory Cytokines in Rats with Periodontitis. In Current Topics in Medicinal Chemistry, 2025-01-01, 25, 5, pp. 645-656. ISSN 15680266. Dostupné na: https://doi.org/10.2174/0115680266302476240510115556. |
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| OCA18. Characteristics of the output's impact on socio-economic practice | The addition of 0.5% HS to laying hen feed had a positive effect on laying rate, daily egg mass, egg weight, feed conversion, and eggshell quality and also had an immunostimulatory effect manifested by the increasing activity of the phagocytes and the B cell immune response. On the other hand, there was an observed increase in the number of enterobacteria in the intestinal contents, and the proportion of T lymphocytes in the blood was significantly reduced. The presented results confirm that HS can be used for the improvement of egg production and quality and for activation of phagocytosis and specific antibody immunity, but their influence on the intestinal microbiota will need to be further studied with respect to a wider range of microbial species inhabiting the digestive tract of laying hens. |
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| OCA19. Characteristics of the output and related activities' impact on the educational process | The results are used in theoretical and practical teaching of students in courses focused on poultry immunity and health safety and egg quality. |
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