| Basic data |
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| OCA1. Surname awarded to the assessed person | Kožárová |
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| OCA2. Name awarded to the assessed person | Ivona |
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| OCA3. Degrees awarded to the assessed person | Assoc. prof. , DVM, PhD |
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| OCA4. Hyperlink to the entry of the person in the Register of university staff | https://www.portalvs.sk/regzam/detail/6056 |
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| OCA5. Area of assessment | study programme food hygiene · III. degree |
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| OCA6. Category of the research/artistic/other output | scientific output |
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| OCA7. Year of publication of the research/artistic/other output | 2012 |
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| OCA8. ID of the record in the Central Registry of Publication Activity (CRPA) or the Central Registry of Artistic Activity (CRAA) | UVL.Košice.0015761 |
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| OCA9. Hyperlink to the record in CRPA or CRAA | http://www.crepc.sk/portal?fn=*recview&uid=739923&pageId=resultform&full=0 |
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| Characteristics of the output that is not registered in CRPA or CRAA |
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| OCA10. Hyperlink to the record in another publicly accessible register, catalogue of research/ artistic/other outputs | https://www.webofscience.com/wos/woscc/full-record/WOS:000303585500006 |
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| OCA11. Characteristics of the output in the format of the CRPA or the CRAA bibliographic record, if the output is not available in a publicly accessible register or catalogue of outputs | ADC TKÁČIKOVÁ, Soňa - KOŽÁROVÁ, Ivona - MAČANGA, Ján - LEVKUT, Martin. Determination of lasalocid residues in the tissues of broiler chickens by liquid chromatography-tandem mass spectrometry. In Food Additives and Contaminants - Part A. ISSN 1944-0049, 2012, vol. 29, č. 5, s. 761-769. (2012: 2.220 - IF, 2.442 - IF 5y, 68 - H-index, 0.906 - SJR, Q1 - SJR Best Q, Q2 - JCR Best Q). |
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| OCA12. Type of the output (if the output is not registered in CRPA or CRAA) | article |
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| OCA13. Hyperlink to the webpage where the output is available (full text, other documentation, etc.) | https://www.tandfonline.com/doi/abs/10.1080/19440049.2011.653987 |
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| OCA14. Characteristics of the author's contribution | The author is the bearer of the main ideas of the scientific work of the postgraduate student (Tkáčiková, S.) and the corresponding author of the scientific output. She is also the bearer of funds for the project from which the scientific output was realized. |
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| OCA15. Annotation of the output with contextual information concerning the description of creative process and the content of the research/artistic/other activity, etc. | Lasalocid is a polyether ionophoric coccidiostat used for the prevention of coccidiosis in poultry at a prescribed concentration and during a certain time interval. Due to a public health concern about the presence of coccidiostat residues in poultry, the aim of the present study was to determine the levels of lasalocid residues in the edible tissues of broiler chickens (breast muscle, thigh muscle, heart, liver, gizzard, kidneys and skin/fat) fed commercially produced feed containing 100 mg kg−1 of lasalocid in complete feed throughout the 5-day withdrawal period (WP). The residues were investigated by liquid chromatography coupled with electrospray ionisation (ESI) tandem mass spectrometry (MS/MS) with triple quadrupole. The limit of detection (LOD) and the limit of quantification (LOQ) of the method were 0.47 and 1.44 µg kg−1, respectively. The average recovery based on the matrix-fortified calibrations for chicken tissues ranged between 79% and 98%. Lasalocid was found to accumulate in the liver, followed by the heart, skin/fat, kidneys, thigh muscle and gizzard. The lowest concentrations of lasalocid residues were found in the breast muscle. On day 5 of the WP, residue concentrations of lasalocid did not decline below the LOQ of the method, but were far below the maximum residue level (MRL) established for lasalocid in poultry from 20 to 100 µg kg−1 by European Commission Regulation (EU) No. 37/2010. The results confirmed that the WP established for lasalocid is sufficient to ensure the decline of its residues in the tissues of broiler chickens to the safe residue level. |
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| Other data |
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| OCA16. Annotation of the output in English | LC-MS/MS is a powerful analytical tool in residue analysis due to its high sensitivity and selectivity. The LC-MS/MS method proved to be a very effective way of determining very low levels of lasalocid residues in the tissues of broiler chickens, thus providing a high level of protection for human health. The method meets all the criteria of Commission Decision 2002/657/EC, and since 2007 it is a statutorily prescribed confirmatory method for routine analysis and the official control of coccidiostat residues in poultry, eggs, rabbit and bovine executed under Council Directive 96/23/EC. |
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| OCA17. List of maximum 5 most significant citations corresponding to the output | PIETRUK, Konrad - OLEJNIK, Malgorzata - POSYNIAK, Andrzej. Coccidiostats in milk: development of a multi-residue method and transfer of salinomycin and lasalocid from contaminated feed. In FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT. ISSN 1944-0049, 2018, vol. 35, no. 8, pp. 1508-1518., Registrované v: WoS
BANKA, W.L. Veterinary Drugs Not Approved for Human Use in the US Food Supply. Evidemce and Policy Implications. In Michigan Journal of Public Affairs, 2018, vol. 15, pp. 5-19.
DASENAKI, Marilena E. - THOMAIDIS, Nikolaos S. Multi-residue methodology for the determination of 16 coccidiostats in animal tissues and eggs by hydrophilic interaction liquid chromatography Tandem mass spectrometry. In FOOD CHEMISTRY. ISSN 0308-8146, 2019, vol. 275, no., pp. 668-680, Registrované v: WoS
RADKO, Lidia - CYBULSKI, Wojciech. The decrease of lasalocid residue in the edible tissues by silymarin supplementation of chicken diet. In Food Additives and Contaminants Part A Chemistry, Analysis, Control, Exposure and Risk Assessment. ISSN 19440049, 2019-05-04, 36, 5, pp. 722-728., Registrované v: Scopus
. LIN, Lu - SONG, Shanshan - WU, Xiaoling - LIU, Liqiang - KUANG, Hua - XIAO, Jing - XU, Chuanlai. Determination of robenidine in shrimp and chicken samples using the indirect competitive enzyme-linked immunosorbent assay and immunochromatographic strip assay. Analyst, 2021, vol. 146, no. 2, pp. 721-729, Registrované v: WoS |
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| OCA18. Characteristics of the output's impact on socio-economic practice | LC-MS/MS is a powerful analytical tool in residue analysis due to its high sensitivity and selectivity. The LC-MS/MS method proved to be a very effective way of determining very low levels of lasalocid residues in the tissues of broiler chickens, thus providing a high level of protection for human health. The method meets all the criteria of Commission Decision 2002/657/EC, and since 2007 it is a statutorily prescribed confirmatory method for routine analysis and the official control of coccidiostat residues in poultry, rabbit, bovine and eggs executed under Council Directive 96/23/EC. |
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| OCA19. Characteristics of the output and related activities' impact on the educational process | The outputs of the scientific article will be used in the implementation of scientific research activities of postgraduate education of doctoral students and as educational material presenting the legislation on official control of residues in products of animal origin. |
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