Targeting the MAPK signaling pathway: implications and prospects of flavonoids in 3P medicine as modulators of cancer cell plasticity and therapeutic resistance in breast cancer patients

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HUANG, Yanjun - LI, Xiaohuan - JIA, Lili - LIU, Juan - NING, Jie. Licochalcone A Induces Mitochondria-Dependent Apoptosis in Hepatocellular Carcinoma Cells via ROS-Regulated Activation of the p38/JNK/MAPK Pathway. In Hepatitis Monthly, 2026-01-01, 26, 1, pp. ISSN 1735143X. Dostupné na: https://doi.org/10.5812/hepatmon-169815.

JUTURU, Pranavi - VADIVEL, Velmurugan. PLANT-DERIVED PHYTOCONSTITUENTS WITH ANTI-BREAST CANCER POTENTIAL: MECHANISTIC INSIGHTS, EVALUATION, AND THERAPEUTIC IMPLICATIONS. In Asian Journal of Pharmaceutical and Clinical Research, 2026-01-01, 19, 1, pp. 57-72. ISSN 09742441. Dostupné na: https://doi.org/10.22159/ajpcr.2026v19i1.57323.

KAMATH, Adithya Jayaprakash - SYAM, Siva - RAJESH, Gowri - RENJINI, Saraswathy - VINOD, Balachandran S. - RAJ, Devarajan Baby Sulekha Ambili - NATH, Lekshmi R. - SHARIFI-RAD, Javad - SETZER, William N. - CALINA, Daniela. Nobiletin reprograms cancer cell fate signaling: PI3K/Akt/mTOR-MAPK crosstalk, NF-kB/STAT3 inhibition and chemosensitization. In CELLULAR SIGNALLING. Vol. 144, no. (2026), pp. Dostupné na: https://doi.org/10.1016/j.cellsig.2026.112549. ISSN 0898-6568.

LI, Fangying - GAO, Zhenhua. Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review). In INTERNATIONAL JOURNAL OF ONCOLOGY. Vol. 68, no. 1 (2026), pp.. Dostupné na: https://doi.org/10.3892/ijo.2025.5825. ISSN 1019-6439.

LI, Yan - HU, Tingting - XU, Wenhao - HUANG, Ruming - KONG, Fanrui - SHE, Yuyan - XIA, Yubei - WU, Yajunyu - GUO, Songru - CAO, Peng - WANG, Ning. Liu Wei formula ameliorates EGFR-induced malignant glioma progression by regulating EGFR/PI3K/AKT pathway and T-cell antitumor immunity. In FRONTIERS IN PHARMACOLOGY, 2026, vol. 17, no., pp. Dostupné na: https://doi.org/10.3389/fphar.2026.1825282.

LIAO, Yu-Hsiang - YANG, Kai-Chien - CHEN, Heng-Jing - SHIH, Ching-Wei - YEH, Yi-Cheng - PENG, Jyun-Yu - LU, Fung-Jou - YANG, Shang-Tzu - CHEN, Ching-Hsein. Combined Curcumin and Doxorubicin Induce Apoptosis via JNK-Dependent MAPK Signaling Independent of TXNDC5 in Human Osteosarcoma Cells. In NUTRIENTS, 2026, vol. 18, no. 8, pp. Dostupné na: https://doi.org/10.3390/nu18081235.

LIU, Ting - SHANG, Jingying - WANG, Jiameng - HAN, Lutuo - YANG, Mingyue - LI, Ruonan - NI, Baoyi - JIANG, Jiakang. Regulatory effects of traditional Chinese medicine on the breast-cancer immune microenvironment. In FRONTIERS IN IMMUNOLOGY. Vol. 16, no. (2026), pp. Dostupné na: https://doi.org/10.3389/fimmu.2025.1706379. ISSN 1664-3224.

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LUO, Jincan - LUO, Jinhai - HAN, Bincheng - XU, Baojun. Dietary anthocyanins and the MAPK signaling pathway: from food sources to molecular mechanisms. In Food Research International, 2026-10-31, 242, pp. ISSN 09639969. Dostupné na: https://doi.org/10.1016/j.foodres.2026.119932.

N, Sanoj Rejinold - JIN, Geun woo - CHOY, Jin Ho. Reprogramming the Tumor Oncobiosphere: Bioactive Nanohybrid Materials for Reversing Therapeutic Pseudo-Resistance. In ACS Omega, 2026-07-21, 11, 28, pp. 40955-40972. Dostupné na: https://doi.org/10.1021/acsomega.6c00998.

PARVEZ, Anwar - SWEETY, Najmun Nahar - ROUF, A. S. M. Abdur - RAHMAN, Md Mahfuzur - NOMAN, Abdullah Al - DEV SHARMA, Pranab - HAQUE, Md. Ekramul - MAMUN, Md Al. Clerodendrum infortunatum (CI) Against Breast Cancer (BC) and Evaluating Its Cytotoxic Activity: A Combined In Silico and In Vivo Approach. CHEMISTRYSELECT. Vol. 11, no. 2 (2026), pp. Dostupné na: https://doi.org/10.1002/slct.202504703. ISSN 2365-6549.

POSANI, Sai Harshita - DIEP, Caroline H. - KRUTILINA, Raisa - PLAYA, Hilaire C. - SEAGROVES, Tiffany N. - BLENIS, John - LANGE, Carol A. Mineralocorticoid and glucocorticoid receptor cooperation drives advanced phenotypes in triple-negative breast cancer. In ENDOCRINOLOGY. Vol. 167, no. 6 (2026), pp. Dostupné na: https://doi.org/10.1210/endocr/bqag055. ISSN 0013-7227.

TENDULKAR, Mugdha - TENDULKAR, Reshma. Unveiling the Influence of Polyphenols on Mitogen-activated Protein Kinases in Cancer. In Cell Biochemistry and Biophysics, 2026-06-01, 84, 2, pp. 1647-1663. ISSN 10859195. Dostupné na: https://doi.org/10.1007/s12013-025-01983-0.

WU, Dan - LAN, Yulong - FENG, Baoyu - DING, Xiong - WU, Chutao - CHEN, Shuohua - MIAO, Congliang - BALMER, Lois - LI, Xingang - WU, Shouling - CHEN, Youren. Synergistic effects of circulating monocyte accumulation and cardiometabolic abnormalities on all-cause mortality: implications for predictive, preventive and personalised medicine. In EPMA JOURNAL. Vol. 17, no. 1 (2026), pp. 193-204. Dostupné na: https://doi.org/10.1007/s13167-026-00439-6. ISSN 1878-5077.

XU, Wenqian - GAO, Ping - WU, Xiuxun - CHEN, Liang - WU, Yong - YUAN, Ming - HU, Junjie - QIU, Zhenpeng. Delivery systems in the diagnosis and treatment of chronic atrophic gastritis: A Three-Level health strategy guided by 3PM. In EPMA JOURNAL. Vol. 17, no. 1 (2026), pp. 163-192. Dostupné na: https://doi.org/10.1007/s13167-026-00436-9. ISSN 1878-5077.

YE, Ziqing - MAYILA, Maimaiti - BU, Na - HAO, Wenhui - MAIMAITIYIMING, Yasen. Epigenetic and epitranscriptomic landscape of phthalate toxicity: Implications for human health and disease. In ENVIRONMENTAL POLLUTION. Vol. 391, no. (2026), pp. Dostupné na: https://doi.org/10.1016/j.envpol.2025.127559. ISSN 0269-7491.