Novel diagnostic tools for identifying cognitive impairment in dogs: behavior, biomarkers, and pathology

BALATONFUREDI, Viktoria - KUBINYI, Eniko. Canine Cognitive Dysfunction from the Perspective of Dog Owners: Recognition, Care, and Emotional Challenges. In ANIMALS, 2026, vol. 16, no. 7, pp. ISSN 2076-2615. Dostupné na: https://doi.org/10.3390/ani16071117.

CIURLI, Luca - GAZZANO, Valentina - CECCHI, Francesca - CURADI, Maria Claudia - GAZZANO, Angelo. Current and emerging biomarkers of cognitive dysfunction in aging dogs: A systematic review. In Journal of Veterinary Behavior, 2026-07-01, 86, pp. 39-56. ISSN 15587878. Dostupné na: https://doi.org/10.1016/j.jveb.2026.04.011.

DEL VALLE, Jacquelyn - NEMZEK, Jean A. - LESTER, Patrick A. - MYERS, Daniel D. - DYSKO, Robert C. Biology and Diseases of Dogs. In Laboratory Animal Medicine, 2026-01-01, pp. 553-607. ISBN [9780443137228, 9780443137211]. Dostupné na: https://doi.org/10.1016/B978-0-443-13721-1.00011-7.

HECHT, Silke - MICHAELS, Jennifer R. Brain Maturation and Aging. In Diagnostic MRI in Dogs and Cats Second Edition, 2026-01-01, pp. 373-382. ISBN [9781032550640, 9781040493700]. Dostupné na: https://doi.org/10.1201/9781003429227-20.

OLBY, Natasha J. - ARAUJO, Joseph A. - GRUEN, Margaret E. - JOHNSON, Phillipa - KUBINYI, Eniko - LANDSBERG, Gary - LATIMER, Caitlin S. - MCGRATH, Stephanie - MCKENZIE, Brennen - MORENO, Julie A. - TARANTINO, Monica - VOLK, Holger. The Canine Cognitive Dysfunction Syndrome Working Group guidelines for diagnosis and monitoring of canine cognitive dysfunction syndrome. In JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 2026, vol. 264, no. 4, pp. ISSN 0003-1488. Dostupné na: https://doi.org/10.2460/javma.25.10.0668.

RIBEIRO, Heloisa Maximo - ALEXANDRE-SILVA, Vanessa - BARBOSA, Klysse Assumpcao - AMORIM, Rogerio Martins - CAGNINI, Didier Quevedo - COMINETTI, Marcia Regina. From companionship to science: the importance of dogs in advancing translational research on Alzheimer's disease a scoping review. In ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS, 2026, vol. 12, no. 1, pp. Dostupné na: https://doi.org/10.1002/trc2.70212.

WINIARCZYK, Dagmara - WINIARCZYK, Mateusz. Proteomic Analysis of Tear Film in Dogs and Cats: Emerging Biomarkers of Cognitive Dysfunction and Neurodegenerative Disorders. In ANIMALS, 2026, vol. 16, no. 6, pp. ISSN 2076-2615. Dostupné na: https://doi.org/10.3390/ani16060930.

ALSULAMI, Abdullatif - BOLAND, Sean W. - MCGRATH, Stephanie - MACLEAN, Evan L. - LATIMER, Caitlin S. - DARVAS, Martin - MORENO, Julie A. Plasma and cerebrospinal fluid biomarkers in aged dogs with cognitive decline. In BMC VETERINARY RESEARCH, 2025, vol. 21, no. 1, pp. Dostupné na: https://doi.org/10.1186/s12917-025-05027-w.

BLANCHARD, Tiphaine - MUGNIER, Amélie - BOULET, Fleur - MEYNADIER, Annabelle - PRIYMENKO, Nathalie. Epidemiological and clinical profiles of young and senior dogs fed a standard diet. In Preventive Veterinary Medicine, 2025-07-01, 240, pp. ISSN 01675877. Dostupné na: https://doi.org/10.1016/j.prevetmed.2025.106537.

CASTRO-FUENTES, Rafael - SOCAS-PÉREZ, Rosy. Unveiling the significance of dog domestication in cognitive dysfunction: Are wolves protected? In Open Veterinary Journal, 2025-01-01, 15, 12, pp. 6126-6145. ISSN 22264485. Dostupné na: https://doi.org/10.5455/OVJ.2025.v15.i12.1.

COLEMAN, Amanda E. - CREEVY, Kate E. - ANDERSON, Rozalyn - REED, May J. - FAJT, Virginia R. - AICHER, Kathleen M. - ATIEE, Genna - BARNETT, Brian G. - BAUMWART, Ryan D. - BOUDREAU, Beth - CUNNINGHAM, Suzanne M. - DUNBAR, Matthew D. - DITZLER, Bobbie - FERGUSON, Anna M. - FORSYTH, Kiersten K. - GAMBINO, Anya N. - GORDON, Sonya G. - HAMMOND, Hillary K. - HOLLAND, Sydney N. - IANNACCONE, Mary K. - ILLING, Kate - KADOTANI, Saki - KNOWLES, Shelby A. - MACLEAN, Evan L. - MARAN, Brian A. - MARKOVIC, Lauren E. - MCGRATH, Stephanie - MELVIN, Rachel L. - MUELLER, Mikaela S. - NELSON, O. Lynne - OLBY, Natasha J. - PANCOTTO, Theresa E. - PARSLEY, Elizabeth - POTTER, Brianna M. - PRESCOTT, Jena O. - SAUNDERS, Ashley B. - SAWYER, Holly M. - SCANSEN, Brian A. - SCHMID, Sarah M. - SMITH, Courtney C. - TJOSTHEIM, Sonja S. - TOLBERT, M. Katherine - TROPF, Melissa A. - VISSER, Lance C. - WARD, Jessica L. - WESSELOWSKI, Sonya R. - WINDSOR, Rebecca C. - YANG, Vicky K. - RUPLE, Audrey - PROMISLOW, Daniel E.L. - KAEBERLEIN, Matt - WILFOND, Benjamin S. - URFER, Silvan R. - SNYDER-MACKLER, Noah M. - SHRAGER, Sandi - SCHWARTZ, Stephen M. - MCCLELLAND, Robyn L. - MA, Jing - LEVINE, Jonathan M. - KERR, Kathleen F. - KARLSSON, Elinor K. - JONLIN, Erica C. - JEFFERY, Unity - FITZPATRICK, Annette L. - CROWDER, Kyle - CASTELHANO, Marta G. - BORENSTEIN, Elhanan - BENTON, Brooke - AKEY, Joshua M. Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project. In Geroscience, 2025-06-01, 47, 3, pp. 2851-2877. ISSN 25092715. Dostupné na: https://doi.org/10.1007/s11357-024-01484-7.

FIGUEROA, Samantha - NUNEZ, Gerardo - BERTIN, Francisca - CANON-JONES, Hernan. Measuring cognitive decline in geriatric dogs using the Canine Dementia Scale in Santiago de Chile. In JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH, 2025, vol. 81, no., pp. ISSN 1558-7878. Dostupné na: https://doi.org/10.1016/j.jveb.2025.08.004.

HENRY, Jamie - UKAI, Masayasu - ANTONAKAKIS, Markos - ZHOU, Tianjian - MORENO, Julie A. - BURZYNSKA, Agnieszka Z. - MCGRATH, Stephanie. Diffusion tensor imaging analysis of aged dogs with and without canine cognitive dysfunction. In BMC Veterinary Research, 2025-12-01, 21, 1, pp. Dostupné na: https://doi.org/10.1186/s12917-025-04973-9.

KANG, Min Hee - JEONG, Woo Phil - NAM, Chan Sik - YOON, Jun Won - CHOI, Dong Min - LEE, Gwang Seob - KIM, Yeon Jin - DAN, Tae Jung - PARK, Hee Myung. Case Report: Ischemic brain infarction and cognitive dysfunction syndrome in an aged dog. In Frontiers in Veterinary Science, 2025-01-01, 12, pp. Dostupné na: https://doi.org/10.3389/fvets.2025.1563798.

KANG, Min-Hee - PARK, Hee-Myung. Cognitive dysfunction in aging dogs and cats: diagnosis and management perspectives. In JOURNAL OF VETERINARY SCIENCE, 2025, vol. 26, no., pp. S125-S138. ISSN 1229-845X. Dostupné na: https://doi.org/10.4142/jvs.25213.

KIM, Sang Hyun - HAO, Jijun. Recent advances in diagnostic and therapeutic strategies for canine cognitive dysfunction. In AMERICAN JOURNAL OF VETERINARY RESEARCH, 2025, vol. 86, no. 8, pp. ISSN 0002-9645. Dostupné na: https://doi.org/10.2460/ajvr.25.02.0053.

MCGRATH, Stephanie - HULL, Emily - DUNBAR, Matthew D. - PRESCOTT, Jena - KEYSER, Amber J. - MACLEAN, Evan - DARVAS, Martin - LATIMER, Caitlin - MORENO, Julie - MACCOSS, Michael J. - KAUFFMAN, Mandy - LITWIN, Paul - CASTELHANO, Marta - KAEBERLEIN, Matt - KEENE, C. Dirk. The companion dog as a translational model for Alzheimer's disease: Development of a longitudinal research platform and post mortem protocols. In ALZHEIMERS & DEMENTIA, 2025, vol. 21, no. 9, pp. ISSN 1552-5260. Dostupné na: https://doi.org/10.1002/alz.70630.

MERBL, Yael - MONDRUS, Ella - HANAEL, Erez - SHAMIR, Merav H. Blood–brain barrier permeability changes in dogs with suspected canine cognitive dysfunction using magnetic resonance imaging subtraction enhancement analysis. In Frontiers in Veterinary Science, 2025-01-01, 12, pp. Dostupné na: https://doi.org/10.3389/fvets.2025.1572286.

SIMON, Katherine E. - GRUEN, Margaret E. - OLBY, Natasha J. Current practices for diagnosis and management of Canine Cognitive Dysfunction Syndrome in the United States. In FRONTIERS IN VETERINARY SCIENCE, 2025, vol. 12, no., pp. Dostupné na: https://doi.org/10.3389/fvets.2025.1685430.

THORSRUD, Joseph A. - EVANS, Katy M. - QUIGLEY, C. Kyle - SRIKANTH, Krishnamoorthy - REVERTER, Antonio - PORTO-NETO, Laercio R. - HUSON, Heather J. Breeding values and index creation for health and behavior traits in Labrador Retriever guide dogs. In FRONTIERS IN VETERINARY SCIENCE, 2025, vol. 12, no., pp. Dostupné na: https://doi.org/10.3389/fvets.2025.1628161.