Polyhydroxybutyrate/Chitosan 3D scaffolds promote in vitro and in vivo chondrogenesis

MAO, Beini - TIAN, Ming - YIN, Yuling - LI, Lang - LI, Jian - WEI, Daixu - FU, Weili. A Novel Injectable Cell-Loaded Hydrogel System for Cartilage Repair: In Vivo and In Vitro Study. In: TISSUE ENGINEERING PART A. – ISSN 1937-3341. – ISSN (online) 1937-335X. – Roč. 32, č. 5-6 (2026), s. 149-162 . Dostupné na: https://doi.org/10.1089/ten.tea.2025.0024. .

YAO, Zeyang - YOU, Xinru - WANG, Xudong - KANG, Yunze - WANG, Liying - ZHANG, Ziji. Stem cell-based hydrogel for the repair and regeneration of cartilage. In CHINESE CHEMICAL LETTERS, 2025, vol. 36, no. 8, pp. ISSN 1001-8417. Dostupné na: https://doi.org/10.1016/j.cclet.2024.110607.

BRODA, Magdalena - YELLE, Daniel J. - SERWAŃSKA-LEJA, Katarzyna. Biodegradable Polymers in Veterinary Medicine—A Review. In Molecules, 2024-02-01, 29, 4, pp. Dostupné na: https://doi.org/10.3390/molecules29040883.

CHEN, Li - YANG, Jianye - CAI, Zhengwei - HUANG, Yanran - XIAO, Pengcheng - WANG, Juan - WANG, Fan - HUANG, Wei - CUI, Wenguo - HU, Ning. Electroactive Biomaterials Regulate the Electrophysiological Microenvironment to Promote Bone and Cartilage Tissue Regeneration. In Advanced Functional Materials, 2024-06-06, 34, 23, pp. ISSN 1616301X. Dostupné na: https://doi.org/10.1002/adfm.202314079.

KHODIR, Wan Kartini Binti Wan Abdul - BIN YUSOF, Mohd Reusmaazran. 3D-scaffold design of biodegradable nanofibers for tissue regeneration and drug delivery. In Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside (Part 2), 2024-02-02, pp. 212-232. Dostupné na: https://doi.org/10.2174/9789815179330124010016.

KABIRKOOHIAN, Anita - BAKHSHI, Hadi - IRANI, Shiva - SHARIFI, Fereshteh. Chemical Immobilization of Carboxymethyl Chitosan on Polycaprolactone Nanofibers as Osteochondral Scaffolds. In Applied Biochemistry and Biotechnology, 2023-06-01, 195, 6, pp. 3888-3899. ISSN 02732289. Dostupné na: https://doi.org/10.1007/s12010-022-03916-6.

KHAN, Muhammad Umar Aslam - ASLAM, Muhammad Azhar - BIN ABDULLAH, Mohd Faizal - HASAN, Anwarul - SHAH, Saqlain A. - STOJANOVIĆ, Goran M. Recent perspective of polymeric biomaterial in tissue engineering– a review. In Materials Today Chemistry, 2023-12-01, 34, pp. Dostupné na: https://doi.org/10.1016/j.mtchem.2023.101818.

LEI, Tao - TONG, Zhicheng - ZHAI, Xinrang - ZHAO, Yushuang - ZHU, Huangrong - WANG, Lu - WEN, Zhengfa - SONG, Binghua. Chondroitin Sulfate Improves Mechanical Properties of Gelatin Hydrogel for Cartilage Regeneration in Rats. In Advanced Biology, 2023-01-01, pp. Dostupné na: https://doi.org/10.1002/adbi.202300249.

REN, Zi Wei - WANG, Ze Yu - DING, Yan Wen - DAO, Jin Wei - LI, Hao Ru - MA, Xue - YANG, Xin Yu - ZHOU, Zi Qi - LIU, Jia Xuan - MI, Chen Hui - GAO, Zhe Chen - PEI, Hua - WEI, Dai Xu. Polyhydroxyalkanoates: the natural biopolyester for future medical innovations. In Biomaterials Science, 2023-07-05, 11, 18, pp. 6013-6034. ISSN 20474830. Dostupné na: https://doi.org/10.1039/d3bm01043k.

GREGORY, David A. - TAYLOR, Caroline S. - FRICKER, Annabelle T. R. - ASARE, Emmanuel - TETALI, Santosh S. - HAYCOCK, John W. - ROY, Ipsita. Polyhydroxyalkanoates and their advances for biomedical applications. In TRENDS IN MOLECULAR MEDICINE, 2022, vol. 28, no. 4, pp. 331-342. ISSN 1471-4914. Dostupné na: https://doi.org/10.1016/j.molmed.2022.01.007.

DE ANGELIS, Elena - SALERI, Roberta - MARTELLI, Paolo - ELVIRI, Lisa - BIANCHERA, Annalisa - BERGONZI, Carlo - PIROLA, Marta - ROMEO, Roberta - ANDRANI, Melania - CAVALLI, Valeria - CONTI, Virna - BETTINI, Ruggero - PASSERI, Benedetta - RAVANETTI, Francesca - BORGHETTI, Paolo. Cultured Horse Articular Chondrocytes in 3D-Printed Chitosan Scaffold With Hyaluronic Acid and Platelet Lysate. In FRONTIERS IN VETERINARY SCIENCE, 2021, vol. 8, no., pp.

GONZALEZ VAZQUEZ, Arlyng G. - BLOKPOEL FERRERAS, Lia A. - BENNETT, Kathleen E. - CASEY, Sarah M. - BRAMA, Pieter A. J. - O'BRIEN, Fergal J. Systematic Comparison of Biomaterials-Based Strategies for Osteochondral and Chondral Repair in Large Animal Models. In ADVANCED HEALTHCARE MATERIALS. ISSN 2192-2640, 2021, vol. 10, no. 20, pp.

KHORASANI, Mohammad Taghi - JOORABLOO, Alireza - ADELI, Hassan - MILAN, Peiman Brouki - AMOUPOUR, Moein. Enhanced antimicrobial and full-thickness wound healing efficiency of hydrogels loaded with heparinized ZnO nanoparticles: In vitro and in vivo evaluation. In INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. ISSN 0141-8130, 2021, vol. 166, no., pp. 200-212.

NUNES DOURADO, Lays Fernanda - PIERUCCI, Amauri - BRETAS ROA, Juan Pedro - DE CARVALHO, Alvaro Dutra. Assessment of implantable drug delivery technology: poly (3-hydroxybutyrate) / polypropylene glycol films containing simvastatin. In MATERIA-RIO DE JANEIRO. ISSN 1517-7076, 2021, vol. 26, no. 4, pp. Dostupné na: https://doi.org/10.1590/S1517-707620210004.1389.

PENG, Liqing - ZHANG, Bin - LUO, Xujiang - HUANG, Bo - ZHOU, Jian - JIANG, Shuangpeng - GUO, Weimin - TIAN, Guangzhao - TIAN, Zhuang - SHEN, Shi - LI, Yangyang - SUI, Xiang - LIU, Shuyun - GUO, Quanyi - LI, Haibo. Small Ruminant Models for Articular Cartilage Regeneration by Scaffold-Based Tissue Engineering. In STEM CELLS INTERNATIONAL. ISSN 1687-966X, 2021, vol. 2021, no., pp. Dostupné na: https://doi.org/10.1155/2021/5590479.

PRYADKO, Artyom - SURMENEVA, Maria A. - SURMENEV, Roman A. Review of Hybrid Materials Based on Polyhydroxyalkanoates for Tissue Engineering Applications. In POLYMERS, 2021, vol. 13, no. 11, pp.

WANG, Zhonggao - ZHANG, Yuanguo - GU, Yongquan - JIAO, Yuhao - WANG, Cong - ZHANG, Chengchao - WANG, Han - FENG, Zengguo. Design and characterization of small-diameter tissue-engineered blood vessels constructed by electrospun polyurethane-core and gelatin-shell coaxial fiber. In BIOENGINEERED. ISSN 2165-5979, 2021, vol. 12, no. 1, pp. 5769-5788.

HU, Qingxi - WU, Chuang - ZHANG, Haiguang. Preparation and Optimization of a Biomimetic Triple-Layered Vascular Scaffold Based on Coaxial Electrospinning. In APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY. ISSN 0273-2289, 2020, vol. 190, no. 3, pp. 1106-1123.

CIPOLLARO, Lucio - CIARDULLI, Maria Camilla - DELLA PORTA, Giovanna - PERETTI, Giuseppe M. - MAFFULLI, Nicola. Biomechanical issues of tissue-engineered constructs for articular cartilage regeneration: in vitro and in vivo approaches. In BRITISH MEDICAL BULLETIN. ISSN 0007-1420, 2019, vol. 132, no. 1, pp. 53-80.